Hodgkins Lymphoma News
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Latest Hodgkins Lymphoma News By Stage
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More AAcute Lymphoblastic Leukemia
Newly Diagnosed Ph+ Acute Lymphoblastic Leukemia Patients May Benefit from Sprycel/Chemotherapy Combination (July 28, 2010)
The initial report of a Phase II study evaluating Sprycel® (dasatinib) combined with chemotherapy for the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) indicates that 94% of patients achieve a complete remission.... Continue Reading
Study Evaluates Anthracycline-related Heart Problems in Childhood Cancer Survivors (May 28, 2010)Children with particular variants of drug-metabolizing genes may be more likely than other children to develop heart problems after low doses of anthracycline chemotherapy. The results of this study will be presented at the 2010 annual meeting of the... Continue Reading
Study Evaluates Anthracycline-related Heart Problems in Childhood Cancer Survivors (May 28, 2010)Children with particular variants of drug-metabolizing genes may be more likely than other children to develop heart problems after low doses of anthracycline chemotherapy. The results of this study will be presented at the 2010 annual meeting of the... Continue Reading
Survivors of Some Childhood Cancers May Face Cognitive Impairment (May 18, 2010)Survivors of non-central nervous system (CNS) childhood cancers reported a statistically and clinically significantly higher rate of neurocognitive impairment than their cancer-free siblings, according to the results of a study published in the Journal... Continue Reading
Study Evaluates Long-term Efficacy of Peripheral Blood Stem Cell Transplant Versus Bone Marrow Transplant (April 29, 2010)For leukemia patients who undergo allogeneic stem cell transplantation, 10-year results indicate that bone-marrow transplantation (BMT) and peripheral blood stem cell transplantation (PBSCT) produce similar rates of overall and leukemia-free survival.... Continue Reading
More Acute Lymphoblastic LeukemiaAcute Myeloid Leukemia
Mylotarg Withdrawn from Market in United States (June 23, 2010)
Mylotarg® (gemtuzumab ozogamicin), a drug used for the treatment of acute myeloid leukemia (AML), will be withdrawn from the U.S. market following a recent clinical trial that raised new concerns about safety and failed to demonstrate clinical benefit. Mylotarg... Continue Reading
Survivors of Some Childhood Cancers May Face Cognitive Impairment (May 18, 2010)Survivors of non-central nervous system (CNS) childhood cancers reported a statistically and clinically significantly higher rate of neurocognitive impairment than their cancer-free siblings, according to the results of a study published in the Journal... Continue Reading
Drinking During Pregnancy May Increase Leukemia Risk in Child (May 13, 2010)According to the results of a study published in Cancer Epidemiology, Biomarkers & Prevention, maternal alcohol consumption during pregnancy may increase the risk of acute myeloid leukemia (AML) in the offspring. Leukemia is a cancer of the blood... Continue Reading
Study Evaluates Long-term Efficacy of Peripheral Blood Stem Cell Transplant Versus Bone Marrow Transplant (April 29, 2010)For leukemia patients who undergo allogeneic stem cell transplantation, 10-year results indicate that bone-marrow transplantation (BMT) and peripheral blood stem cell transplantation (PBSCT) produce similar rates of overall and leukemia-free survival.... Continue Reading
Mylotarg Effective for Older Intermediate-risk AML Patients (April 7, 2010)Researchers from the University of Pittsburgh have reported that single-agent Mylotarg® (gemtuzumab ozogamicin) resulted in a complete remission (CR) rate of 30% in patients 70 years or older with newly diagnosed acute myeloid leukemia (AML). The... Continue Reading
More Acute Myeloid LeukemiaAcute Promyelocytic Leukemia
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More Acute Promyelocytic LeukemiaAdjuvant (I-III, A-C) Colon Cancer
Antibiotic Sponge Ineffective at Preventing Surgical Infection (August 12, 2010)
Patients undergoing colorectal surgery are reported to experience an increased incidence of surgical-site infection with the addition of a gentamicin-collagen sponge enclosed at the surgery site. These findings were recently published in the New England... Continue Reading
Potential Role for Oncotype DX Colon Cancer Test in Stage III Cancer (June 10, 2010)The Oncotype DX® colon cancer test, which is currently available for treatment planning in Stage II colon cancer, may also predict recurrence risk in Stage III colon cancer. These results were presented at the 2010 annual meeting of the American Society... Continue Reading
Erbitux Does Not Improve Survival in Stage III Colon Cancer with Normal KRAS (June 8, 2010)The addition of Erbitux® (cetuximab) to standard adjuvant chemotherapy in patients with stage III colon cancer who have normal KRAS gene activity does not improve survival, according to the results of a Phase III study presented at the 2010 annual meeting... Continue Reading
Most Survivors of Lung and Colorectal Cancer Keep Their Jobs (April 14, 2010)Among people diagnosed with nonmetastatic lung or colorectal cancer, the majority return to work, according to a study recently published in Journal of Clinical Oncology. Those who do leave the workforce tend to have worse prognoses and lower socioeconomic... Continue Reading
Older Stage III Colon Cancer Patients Not Being Treated According to Evidence-based Recommendations (March 25, 2010)The treatment of Stage III colon cancer does not always follow evidence-based recommendations, especially for older patients, according to the results of an observational study recently published in the Journal of the American Medical Association.[1] Stage... Continue Reading
More Adjuvant (I-III, A-C) Colon CancerAdult Acute Lymphoblastic Leukemia
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More Adult Acute Lymphoblastic LeukemiaAdvanced Stage Hodgkin's Lymphoma
Hodgkin’s Survivors at Increased Risk of Stroke (June 24, 2009)
Hodgkin’s Survivors at Increased Risk of Stroke Patients who have been treated with radiation therapy for Hodgkin’s lymphoma have an elevated risk of stroke. These results were published in the Journal of the National Cancer Institute. Hodgkin’s... Continue Reading
Better Prognosis for Patients with Lymphocyte-predominant Hodgkin’s Lymphoma (March 8, 2009)Better Prognosis for Patients with Lymphocyte-predominant Hodgkin’s Lymphoma A recent study compared lymphocyte-predominant Hodgkin’s lymphoma (LPHL) and classical Hodgkin’s lymphoma (cHL) in order to define differences in patient characteristics... Continue Reading
Hodgkin’s Lymphoma Survivors May Be at Risk for Secondary Cancer (March 8, 2009)Hodgkin’s Lymphoma Survivors May Be at Risk for Secondary Cancer Hodgkin’s lymphoma survivors may be at risk for secondary cancer. These findings were recently reported in the British Journal of Cancer. Hodgkin’s lymphoma is a cancer... Continue Reading
The American Society of Clinical Oncology 2008: Advances in Treatment of Lymphoma and Chronic Lymphocytic Leukemia (March 8, 2009)The American Society of Clinical Oncology 2008: Advances in Treatment of Lymphoma and Chronic Lymphocytic Leukemia At the 2008 meeting of the American Society of Clinical Oncology (ASCO), there were more than 100 abstracts devoted to the treatment of... Continue Reading
More Advanced Stage Hodgkin's LymphomaAdvisory Complementary Alternative Medicine
Combination of Herceptin® with Non–anthracycline-based Chemotherapy Appears to Be Effective (December 15, 2009)
Among women with early, HER2-positive breast cancer, the addition of Herceptin® (trastuzumab) to adjuvant chemotherapy reduces the risk of cancer recurrence and improves survival. Herceptin provides a benefit in combination with either anthracycline-... Continue Reading
More Advisory Complementary Alternative MedicineAggressive/Intermediate Grade Non-Hodgkin's Lymphoma
Survivors of Some Childhood Cancers May Face Cognitive Impairment (May 18, 2010)
Survivors of non-central nervous system (CNS) childhood cancers reported a statistically and clinically significantly higher rate of neurocognitive impairment than their cancer-free siblings, according to the results of a study published in the Journal... Continue Reading
Children and Teens Have Better NHL Survival than Young Adults (March 15, 2010)Even after accounting for stage at diagnosis and subtype of non-Hodgkin’s lymphoma (NHL), children and teens with NHL have better survival than young adults with NHL. These results were published in the Archives of Pediatrics and Adolescent Medicine. Non-Hodgkin’s... Continue Reading
Advances in the Treatment of Aggressive Non-Hodgkin’s Lymphoma (March 8, 2009)Advances in the Treatment of Aggressive Non-Hodgkin’s Lymphoma A Report from the 2008 Meeting of the American Society of Hematology Rituxan and Intensive HyperCVAD Chemotherapy for Mantle Cell Lymphoma Mantle cell lymphoma is a subset of non-Hodgkin’s... Continue Reading
New and Novel Agents for the Treatment of Non-Hodgkin’s Lymphoma: A Report from the 2008 Meeting of the American Society of Hematology (March 8, 2009)New and Novel Agents for the Treatment of Non-Hodgkin’s Lymphoma: A Report from the 2008 Meeting of the American Society of Hematology The 2008 ASH meeting featured several reports of new agents that are showing promise in the treatment of Non-Hodgkin’s... Continue Reading
Dose Intensity Associated with Survival in Non-Hodgkin’s Lymphoma (March 8, 2009)Dose Intensity Associated with Survival in Non-Hodgkin’s Lymphoma Relative dose intensity (RDI) remains a key factor in the outcomes of patients with non-Hodgkins lymphoma (NHL). These results have been validated in several multicenter clinical... Continue Reading
More Aggressive/Intermediate Grade Non-Hodgkin's LymphomaAll Cancer Types
Guidelines Encourage Exercise During and After Cancer Treatment (June 7, 2010)
Cancer patients who’ve been told to rest and avoid exercise can—and should—find ways to be physically active both during and after treatment, according to new national guidelines. Kathryn Schmitz, PhD, MPH, an associate professor of Epidemiology... Continue Reading
Cancer Caregivers Devote Substantial Time and Effort (September 9, 2009)On average, informal caregivers of cancer patients devote more than eight hours per day to caregiving. These results were published in Cancer. Informal caregiving is an important part of cancer management. Family and friends often spend considerable time... Continue Reading
September Is National Leukemia and Lymphoma Awareness Month (August 28, 2009)As the month of September brings leukemia and lymphoma into focus, it’s time to increase public understanding of these diseases, including their prevalence, approaches to screening and prevention, treatment options, and resources that offer updated... Continue Reading
More All Cancer TypesAllogeneic Stem Cell Transplant
Complementary Therapy for Children Undergoing Stem Cell Transplant (July 19, 2010)
Complementary therapies such as massage and humor therapy may not help children cope with the potential emotional distress associated with stem cell transplantation, according to findings recently reported in Cancer. Stem cell transplantation involves... Continue Reading
Statins May Reduce Acute Graft-versus-host Disease (March 8, 2009)Statins May Reduce Acute Graft-versus-host Disease Researchers from Ohio State University have reported that statins may reduce the risk of developing acute graft-versus-host disease (GVHD) among patients who undergo allogeneic stem cell transplants.... Continue Reading
Stem Cell Transplant Procedures Vary Throughout the World (March 8, 2009)Stem Cell Transplant Procedures Vary Throughout the World Stem cell transplant practices vary substantially among physicians treating adults and children with hematologic malignancies (cancers of the blood or bone marrow such as leukemias and lymphomas).... Continue Reading
More Allogeneic Stem Cell TransplantAlphabetical Sort
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More Alphabetical SortAlternative Medical Systems Complementary Alternative Medicine
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More Alternative Medical Systems Complementary Alternative MedicineAnal Cancer
Immunosuppression Increases Risk of HPV-related Cancers in AIDS Patients (August 20, 2009)
The risk of HPV-related cancers is elevated among AIDS patients. This risk continues to increase as patients’ immune systems become more compromised, according to the results of a study published in the Journal of the National Cancer Institute.[1] Human... Continue Reading
More Anal CancerAutologous Stem Cell Transplant
Complementary Therapy for Children Undergoing Stem Cell Transplant (July 19, 2010)
Complementary therapies such as massage and humor therapy may not help children cope with the potential emotional distress associated with stem cell transplantation, according to findings recently reported in Cancer. Stem cell transplantation involves... Continue Reading
Kepivance Reduces Toxicity of High-dose Therapy for Multiple Myeloma (March 24, 2010)Among patients undergoing high-dose therapy and autologous stem cell transplantation for multiple myeloma, a three-day short course of Kepivance® (palifermin) reduces the toxicity of treatment. These results were published in the Annals of Oncology. Multiple... Continue Reading
Stem Cell Transplant Procedures Vary Throughout the World (March 8, 2009)Stem Cell Transplant Procedures Vary Throughout the World Stem cell transplant practices vary substantially among physicians treating adults and children with hematologic malignancies (cancers of the blood or bone marrow such as leukemias and lymphomas).... Continue Reading
More Autologous Stem Cell TransplantB
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More BBarrett's Esophagus Esophageal Cancer
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More Barrett's Esophagus Esophageal CancerBiologic-Orthomolecular Therapies Complementary Alternative Medicine
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More Biologic-Orthomolecular Therapies Complementary Alternative MedicineBiological Therapy
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More Biological TherapyBladder Cancer
Components of Processed Meat May Increase Risk of Bladder Cancer (August 10, 2010)
People who consume a large amount of nitrite and nitrate from processed meat may be at an increased risk for developing bladder cancer, according to a study published in Cancer. Bladder cancer is diagnosed in as many as 60,000 individuals annually in... Continue Reading
Study Evaluates Incidence of Lymphedema Resulting from Cancer Treatment (August 9, 2010)A systematic review of 47 studies evaluating treatment for melanoma, head and neck cancer, genitourinary cancers, gynecologic cancers, and sarcoma indicates that lymphedema is a common side effect of treatment for these diseases. These findings were recently... Continue Reading
Painters May Have Higher Risk of Bladder Cancer (July 29, 2010)Occupational exposures appear to increase bladder cancer risk in painters, according to a study published in Occupational and Environmental Medicine. Workers in certain occupations may face an increased risk of cancer due to exposures that they encounter... Continue Reading
Exposure to Aromatic Amines Poses Long-term Risk of Bladder Cancer (June 25, 2010)Workers exposed to aromatic amines continued to experience an increased risk of bladder cancer even 30 years after exposure, according to the results of a follow-up study published in the Journal of the National Cancer Institute.[1] Aromatic amines are... Continue Reading
Vitamins C, D, and E Don’t Reduce Risk of Bladder Cancer (June 7, 2010)Long-term use of vitamin C, vitamin D, or vitamin E does not appear to reduce the risk of bladder cancer. These results were presented at the 2010 annual meeting of the American Urological Association. Each year in the United States, close to 53,000 men... Continue Reading
More Bladder CancerBone Cancer
Denosumab Active Against Giant Cell Tumor of Bone (February 11, 2010)
In a Phase II clinical trial, denosumab produced high rates of tumor response among patients with recurrent or unresectable giant cell tumors of bone. These results were published in Lancet Oncology. Denosumab is an investigational drug that targets... Continue Reading
Denosumab Produces Promising Results Against Giant Cell Tumor of the Bone (June 5, 2009)Denosumab Produces Promising Results Against Giant Cell Tumor of the Bone In a Phase II clinical trial, 86% of patients with giant cell tumor of the bone responded to treatment with the investigational targeted therapy denosumab. These results were presented... Continue Reading
More Bone CancerBrain Cancer
Cell Phone Towers and Childhood Cancer Risk (July 1, 2010)
Recent findings indicate that children who are exposed to radiofrequency fields from cell phone towers before birth do not have an increased risk of early childhood cancer. This study was published in the British Medical Journal. The health effects—notably,... Continue Reading
Novel Approach Shows Promise for Glioblastoma (June 16, 2010)A new non-invasive treatment has shown promising results in patients with recurrent glioblastoma when compared with the best standard chemotherapy regimens, according to the results of a Phase III study presented at the 2010 annual meeting of the American... Continue Reading
Rindopepimut with Temodar Appears Promising in Newly Diagnosed Glioblastoma Multiforme (June 14, 2010)Maintenance therapy with rindopepimut (CDX-110) combined with Temodar® (temozolomide) resulted in a 70% progression-free rate at 5.5 months for newly diagnosed patients with glioblastoma multiforme (GBM). These findings were recently presented at the... Continue Reading
Recurrent High-grade Glioma Patients May Benefit from Hypofractionated Stereotactic Radiation Therapy (June 1, 2010)Patients with recurrent, high-grade glioma who were treated with hypofractionated stereotactic radiation therapy (H-SRT) experienced minimal side effects and a median survival of 11 months. These results were recently published in the Journal of Clinical... Continue Reading
Optimal Outcomes with Vascular Endothelial Growth Factor (VEGF) Inhibitors Require Appropriate Hypertension Assessment, Monitoring, and Management (May 28, 2010)An expert panel provided consensus recommendations for appropriate prevention, surveillance and treatment of hypertension (high blood pressure) in patients treated with vascular endothelial growth factor (VEGF) signaling pathway inhibitors. These recommendations... Continue Reading
More Brain CancerBreast Cancer
Preventive Surgery Reduces Cancer Risk in Women with BRCA1 or BRCA2 Mutations (September 8, 2010)
Among women with a BRCA1 or BRCA2 gene mutation, prophylactic mastectomy (preventive removal of the breasts) reduces the risk of getting breast cancer. Prophylactic salpingo-oophorectomy (preventive removal of the fallopian tubes and ovaries) reduces... Continue Reading
Alcohol Linked with Lobular Breast Cancer (September 3, 2010)Although alcohol is a well-established risk factor for breast cancer, it may be more strongly linked with lobular breast cancer than with ductal breast cancer. These results were published in the Journal of the National Cancer Institute. Research suggests... Continue Reading
Additional Research on Menopausal Hormone Therapy and Breast Cancer (August 24, 2010)A recent study of menopausal hormone therapy and risk of breast cancer reported that risk may vary by body weight and the type of hormone therapy. These results were published in Cancer Epidemiology, Biomarkers, & Prevention. As women reach menopause... Continue Reading
Study Evaluates Impact of Lymph Node Removal in Early-stage Breast Cancer (August 13, 2010)Early-stage breast cancer patients without evidence of cancer in their sentinel lymph node who did not have additional lymph nodes removed report fewer side effects to the arm and breast than patients who undergo additional lymph node removal. These findings... Continue Reading
Breast Density and Hormone Therapy Add to Breast Cancer Risk (August 4, 2010)Postmenopausal women with high breast density are at an increased risk of developing breast cancer, according to the results of a study published in the Journal of Clinical Oncology.[1] This risk increases with the use of hormone therapy. Breast density... Continue Reading
More Breast CancerC
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More CCancer Dictionary
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More Cancer DictionaryCarcinoma In Situ Breast cancer
Racial Disparity in Breast Cancer Outcomes Among Underinsured (June 30, 2010)
Underinsured African-Americans have worse breast cancer survival outcomes than their underinsured White counterparts, according to the results of a study published early online in the Journal of the National Caner Institute.[i] The disparity in breast... Continue Reading
Study Explores Risk of Invasive Breast Cancer in Women with DCIS (May 10, 2010)Among women with breast ductal carcinoma in situ (DCIS), evaluation of three molecular markers in a sample of DCIS tissue may provide information about the subsequent risk of invasive breast cancer. These results were published in the Journal of the... Continue Reading
Delay in Radiation Therapy Increases Risk of Breast Cancer Recurrence (April 1, 2010)Among older women who undergo breast-conserving surgery (lumpectomy) for early breast cancer, a longer interval between surgery and the start of radiation therapy increases the risk of local cancer recurrence. These results were published in the British... Continue Reading
Acupuncture Reduces Hot Flashes in Breast Cancer Patients (January 4, 2010)Among women treated with hormonal therapy for breast cancer, acupuncture and Effexor® (venlafaxine) were similarly effective at reducing the frequency of hot flashes. These results were published in the Journal of Clinical Oncology. The majority of breast... Continue Reading
Young Women with DCIS Have Higher Risk of Recurrence (October 12, 2009)After treatment of breast ductal carcinoma in situ (DCIS) with breast-conserving surgery and radiation therapy, women age 44 or younger have a higher rate of recurrence than older women. These results were presented at the ASCO 2009 Breast Cancer Symposium. Ductal... Continue Reading
More Carcinoma In Situ Breast cancerCervical Cancer
Study Evaluates Incidence of Lymphedema Resulting from Cancer Treatment (August 9, 2010)
A systematic review of 47 studies evaluating treatment for melanoma, head and neck cancer, genitourinary cancers, gynecologic cancers, and sarcoma indicates that lymphedema is a common side effect of treatment for these diseases. These findings were recently... Continue Reading
HPV Vaccine Protects Against Genital Warts and Precancerous Growths (July 30, 2010)Results from a recent international study indicate that the vaccine Gardasil® (quadrivalent human papillomavirus [types 6, 11, 16, 18] recombinant vaccine) protects against genital warts and low-grade precancerous changes to the cervix, vulva, and vagina.... Continue Reading
Many Physicians Fail to Adhere to New Cervical Cancer Screening Guidelines (July 12, 2010)Apparently, old habits die hard: less than one-third of physicians report compliance with the updated guidelines for cervical cancer screening that suggest longer intervals between screening for women with normal test results. The results of this survey... Continue Reading
More Than Half of Young Adults in New Relationships Infected with HPV (April 26, 2010)More than half of young adults in a new sexual relationship are infected with human papillomavirus (HPV), and of those 44% were infected with an HPV type that causes cancer, according to the results of a groundbreaking study called the HITCH Cohort... Continue Reading
Cervical Vaccine Provides Little Benefit for Older Women (March 4, 2010)Women over the age of 40 are not likely to benefit from a vaccine designed to prevent human papillomavirus (HPV), according to the results of a study published in the Journal of the National Cancer Institute.1 HPV has been shown to cause cervical cancer. Human... Continue Reading
More Cervical CancerChemotherapy
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More ChemotherapyChildhood Acute Lymphoblastic Leukemia
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More Childhood Acute Lymphoblastic LeukemiaChronic Lymphoblastic Leukemia
Survivors of Some Childhood Cancers May Face Cognitive Impairment (May 18, 2010)
Survivors of non-central nervous system (CNS) childhood cancers reported a statistically and clinically significantly higher rate of neurocognitive impairment than their cancer-free siblings, according to the results of a study published in the Journal... Continue Reading
Arzerra, Fludara, and Cytoxan Promising for Previously Untreated CLL (February 1, 2010)The combination of Arzerra™ (ofatumumab), Fludara® (fludarabine), and Cytoxan® (cyclophosphamide) shows promising effectiveness in the initial treatment of chronic lymphocytic leukemia (CLL). These results were presented at the 2009 annual meeting... Continue Reading
Treanda® and Rituxan® Effective Initial Therapy for CLL (January 5, 2010)According to the results of a Phase II clinical trial, the combination of Treanda® (bendamustine) and Rituxan® (rituximab) is effective and safe for the initial treatment of patients with advanced chronic lymphocytic leukemia (CLL). These results were... Continue Reading
Arzerra™ Approved for Refractory Chronic Lymphocytic Leukemia (October 28, 2009)The targeted therapy Arzerra™ (ofatumumab) has been granted accelerated approval by the U.S. Food and Drug Administration for treatment of patients with chronic lymphocytic leukemia (CLL) that is refractory to Fludara® (fludarabine) and Campath® (alemtuzumab). Chronic... Continue Reading
FCR-Lite Is Safe and Effective in Previously Untreated CLL (March 8, 2009)FCR-Lite Is Safe and Effective in Previously Untreated CLL FCR-Lite, a drug regimen that consists of Fludara® (fludarabine), Cytoxan® (cyclophosphamide), and Rituxan® (rituximab), is highly effective in previously untreated patients with chronic lymphocytic... Continue Reading
More Chronic Lymphoblastic LeukemiaChronic Lymphocytic Leukemia
Fludara plus Rituxan Extends Survival in CLL (April 6, 2010)
Patients with untreated chronic lymphocytic leukemia experienced prolonged survival when treated with Fludara® (fludarabine) plus Rituxan® (rituximab) (delivered either concurrently or sequentially), according to the results of a study presented... Continue Reading
Rituxan Approved for Chronic Lymphocytic Leukemia (February 24, 2010)The U.S. Food and Drug Administration (FDA) has expanded the approval of Rituxan® (rituximab) to include the treatment of certain patients with chronic lymphocytic leukemia. Chronic lymphocytic leukemia (CLL) is the most common adult leukemia with... Continue Reading
Arzerra™ Approved for Refractory Chronic Lymphocytic Leukemia (October 28, 2009)The targeted therapy Arzerra™ (ofatumumab) has been granted accelerated approval by the U.S. Food and Drug Administration for treatment of patients with chronic lymphocytic leukemia (CLL) that is refractory to Fludara® (fludarabine) and Campath® (alemtuzumab). Chronic... Continue Reading
Abnormal Cells Identified in Blood Years Before Diagnosis of CLL (March 9, 2009)According to the results of a study published in the New England Journal of Medicine, chronic lymphocytic leukemia (CLL) appears to be preceded by a condition known as monoclonal B-cell lymphocytosis (MBL). Chronic lymphocytic leukemia is the most common... Continue Reading
More Chronic Lymphocytic LeukemiaChronic Myeloid Leukemia
Tasigna Approved for Initial Treatment of Chronic Myeloid Leukemia (June 22, 2010)
The U.S. Food and Drug Administration has expanded the approval of Tasigna® (nilotinib) to include the initial treatment of patients with Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase. Each year in the United States, approximately... Continue Reading
Sprycel May Be More Effective than Gleevec for Initial Treatment of CML (June 7, 2010)In the initial treatment of chronic myeloid leukemia (CML), Sprycel® (dasatinib) produces higher response rates than Gleevec® (imatinib). These results were presented at the 2010 annual meeting of the American Society of Clinical Oncology. Each year... Continue Reading
Survivors of Some Childhood Cancers May Face Cognitive Impairment (May 18, 2010)Survivors of non-central nervous system (CNS) childhood cancers reported a statistically and clinically significantly higher rate of neurocognitive impairment than their cancer-free siblings, according to the results of a study published in the Journal... Continue Reading
Study Evaluates Long-term Efficacy of Peripheral Blood Stem Cell Transplant Versus Bone Marrow Transplant (April 29, 2010)For leukemia patients who undergo allogeneic stem cell transplantation, 10-year results indicate that bone-marrow transplantation (BMT) and peripheral blood stem cell transplantation (PBSCT) produce similar rates of overall and leukemia-free survival.... Continue Reading
Tasigna May Be More Effective than Gleevec for Initial Treatment of CML (January 28, 2010)In the initial treatment of chronic myeloid leukemia (CML), Tasigna® (nilotinib) appears to produce higher response rates than Gleevec® (imatinib) 400 mg/day. These results were presented at the 2009 meeting of the American Society of Hematology... Continue Reading
More Chronic Myeloid LeukemiaColon Cancer
Antibiotic Sponge Ineffective at Preventing Surgical Infection (August 12, 2010)
Patients undergoing colorectal surgery are reported to experience an increased incidence of surgical-site infection with the addition of a gentamicin-collagen sponge enclosed at the surgery site. These findings were recently published in the New England... Continue Reading
Screening Rates Among Older Americans (July 15, 2010)More older Americans are undergoing screening for colon cancer, but the rates for breast cancer screening remain the same, according to a government report released on July 6, 2010.[1] The best “treatment” of cancer is preventing its occurrence in... Continue Reading
Radioembolization plus Fluorouracil Active in Colorectal Cancer Patients with Liver Metastases (July 2, 2010)Radioembolization plus the chemotherapy agent fluorouracil slows cancer progression for colorectal cancer patients whose disease has progressed following prior treatment with chemotherapy and have metastases limited to the liver. These findings were recently... Continue Reading
Potential Role for Oncotype DX Colon Cancer Test in Stage III Cancer (June 10, 2010)The Oncotype DX® colon cancer test, which is currently available for treatment planning in Stage II colon cancer, may also predict recurrence risk in Stage III colon cancer. These results were presented at the 2010 annual meeting of the American Society... Continue Reading
Erbitux Does Not Improve Survival in Stage III Colon Cancer with Normal KRAS (June 8, 2010)The addition of Erbitux® (cetuximab) to standard adjuvant chemotherapy in patients with stage III colon cancer who have normal KRAS gene activity does not improve survival, according to the results of a Phase III study presented at the 2010 annual meeting... Continue Reading
More Colon CancerComplementary Alternative Medicine
Fish Oil Linked to Reduction in Breast Cancer Risk (July 9, 2010)
A recent study suggests that regular use of fish oil supplements may reduce the risk of breast cancer. These findings were published in the journal of Cancer Epidemiology, Biomarkers & Prevention.[1] Dietary supplements are a booming business—Americans... Continue Reading
Use of Complementary and Alternative Medicine Common in Pediatric Cancer Patients (April 8, 2010)Pediatric cancer patients commonly use complementary and alternative medicine (CAM), according to a review article recently published in the journal Pediatrics.[1] The landscape of medicine has been dramatically changing over the past several decades.... Continue Reading
Women&Cancer Magazine Features Paula Zahn on Spring 2008 Cover (March 8, 2009)Women&Cancer Magazine Features Paula Zahn on Spring 2008 Cover March 17, 2008 Press Contact: Diana Price dprice@omnihealthmedia.com (208) 727-2108, ext. 202 March 17, 2008-Zahn Appears on Women&Cancer cover, Spring 2008 News anchor... Continue Reading
More Complementary Alternative MedicineCorticosteroid
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More CorticosteroidD
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More DDrug Dictionary
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More Drug DictionaryE
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More EEarly Stage Hodgkin's Lymphoma
Reduced-intensity Treatment May be Effective for Early Hodgkin’s Lymphoma (August 27, 2010)
Among patients with early-stage Hodgkin’s lymphoma and a favorable prognosis, it may be possible to reduce the number of chemotherapy cycles and the dose of radiation therapy without adversely affecting outcome. The results of this study were published... Continue Reading
Study Confirms that Radiation Therapy Is Not Necessary in Patients with Favorable, Limited-stage Hodgkin’s Lymphoma (April 5, 2010)Researchers from the Dana-Farber Cancer Center have confirmed prior studies that indicate chemotherapy alone is safe and effective for the treatment of early-stage Hodgkin’s Lymphoma in appropriate patients. The details of this study were published... Continue Reading
Hodgkin’s Survivors at Increased Risk of Stroke (June 24, 2009)Hodgkin’s Survivors at Increased Risk of Stroke Patients who have been treated with radiation therapy for Hodgkin’s lymphoma have an elevated risk of stroke. These results were published in the Journal of the National Cancer Institute. Hodgkin’s... Continue Reading
Formaldehyde Exposure May Increase Risk of Blood and Lymphatic Cancers (June 23, 2009)Formaldehyde Exposure May Increase Risk of Blood and Lymphatic Cancers Industrial workers who are exposed to formaldehyde may be at an increased risk of dying from blood and lymphatic cancers, particularly myeloid leukemia but also Hodgkin’s lymphoma... Continue Reading
Differences in IMRT Radiation Doses May Complicate Study Results in Lymphomas (March 8, 2009)Differences in IMRT Radiation Doses May Complicate Study Results in Lymphomas Differences between the prescribed dose of radiation in intensity modulated radiation therapy (IMRT) and the dose that’s actually delivered may make comparison studies... Continue Reading
More Early Stage Hodgkin's LymphomaEarly Stage I-II (A-B) Prostate Cancer
Death from Other Causes Among Men with Early-stage Prostate Cancer (August 26, 2010)
Among men with early-stage prostate cancer, assessment of other health problems may help guide prostate cancer treatment decisions; men who are likely to die of causes other than prostate cancer may not benefit from aggressive prostate cancer treatment.... Continue Reading
Study Explores Prostate Cancer Among Men with Low PSA Levels (July 30, 2010)In a large U.S. cancer database, 14% of prostate cancer diagnoses occurred among men with a prostate-specific antigen (PSA) level of 4.0 ng/mL or lower. More than half of these men had cancer that was considered “low-risk,” but roughly three-quarters... Continue Reading
Statins May Reduce Risk of Prostate Cancer Recurrence (July 2, 2010)Statin use may reduce the risk of prostate cancer recurrence among men who have undergone a radical prostatectomy. These findings were recently published in the journal Cancer.[1] Statins are cholesterol-lowering drugs; they are the most commonly prescribed... Continue Reading
Watchful Waiting May Be Sufficient in Low-risk Prostate Cancer (June 30, 2010)Active surveillance—sometimes referred to as “watchful waiting”—may be acceptable treatment for low-risk prostate cancer, according to the results of a study published early online in the Journal of the National Cancer Institute.[1] Men with early-stage... Continue Reading
External Beam Radiation Raises Risk of Hip Fracture in Prostate Cancer (June 8, 2010)Men treated with external beam radiation therapy for prostate cancer may have an increased risk of hip fracture, according to data presented at the 2010 Annual Scientific Meeting of the American Urological Association. Radiation therapy is a commonly... Continue Reading
More Early Stage I-II (A-B) Prostate CancerEsophageal Cancer
Reassuring Findings Regarding Oral Bisphosphonates and Esophageal Cancer (August 23, 2010)
Oral bisphosphonates—drugs commonly used to prevent or treat osteoporosis—do not appear to increase the risk of esophageal cancer. These results were published in the Journal of the American Medical Association. Osteoporosis—a condition characterized... Continue Reading
Chemoradiotherapy plus Surgery Improves Esophageal Cancer Survival (July 19, 2010)Among patients with cancer of the esophagus or esophagogastric junction, treatment with chemotherapy and radiation therapy prior to surgery resulted in better overall survival than surgery alone. The results of this Phase III clinical trial were presented... Continue Reading
High Circulating Vitamin D Levels Don’t Reduce Risk of Less Common Cancers (July 13, 2010)High levels of vitamin D in the bloodstream do not appear to reduce the risk of seven less common cancers: endometrial, esophageal, stomach, ovarian, pancreatic, kidney, and non-Hodgkin’s lymphoma. In fact, there was a suggestion that people with the... Continue Reading
Depression May Persist With Metastatic Cancer (May 27, 2010)A substantial number of patients with metastatic cancer may suffer from depression which tends to persist and grow more severe toward the end of life, according to the results of a study published early online in the Journal of Clinical Oncology.[1] While... Continue Reading
Excess Body Weight Linked with More Than 100,000 New Cancer Diagnoses Each Year in U.S. (November 9, 2009)According to estimates from the American Institute for Cancer Research (AICR), excess body weight may be responsible for more than 100,000 new cancer diagnoses each year in the United States. Excess body weight is increasingly recognized as a risk factor... Continue Reading
More Esophageal CancerEwing's Sarcoma Overview
Children with Ewing’s Sarcoma or Astrocytoma Most Likely to Experience Late Recurrence (February 19, 2010)
Late recurrence of childhood cancers appears to occur most often in Ewing’s sarcoma and astrocytoma, according to the results of a study published in the Journal of the National Cancer Institute. As cancer treatment has improved and evolved, the number... Continue Reading
More Ewing's Sarcoma OverviewExtensive Lung Cancer - Small Cell
Depression May Persist With Metastatic Cancer (May 27, 2010)
A substantial number of patients with metastatic cancer may suffer from depression which tends to persist and grow more severe toward the end of life, according to the results of a study published early online in the Journal of Clinical Oncology.[1] While... Continue Reading
Most Survivors of Lung and Colorectal Cancer Keep Their Jobs (April 14, 2010)Among people diagnosed with nonmetastatic lung or colorectal cancer, the majority return to work, according to a study recently published in Journal of Clinical Oncology. Those who do leave the workforce tend to have worse prognoses and lower socioeconomic... Continue Reading
November Is National Lung Cancer Awareness Month (November 6, 2009)As the month of November brings lung cancer into focus, it’s time to increase public understanding of the disease, including its prevalence, approaches to screening and prevention, treatment options, and resources that offer updated lung cancer information... Continue Reading
Thalidomide Doesn’t Benefit Patients with Small Cell Lung Cancer (July 22, 2009)Treatment with a combination of thalidomide and chemotherapy did not improve survival among patients with small cell lung cancer, and resulted in a higher risk of blood clots than treatment with chemotherapy alone. The results of this study were published... Continue Reading
VePesid®/Platinol® Remains Standard-of-care for Small Cell Lung Cancer (March 8, 2009)VePesid®/Platinol® Remains Standard-of-care for Small Cell Lung Cancer For patients diagnosed with extensive-stage small-cell lung cancer (SCLC), the standard-of-care remains the chemotherapy combination of VePesid® (etoposide) and Platinol® (cisplatin).... Continue Reading
More Extensive Lung Cancer - Small CellF
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More FFollicular Lymphoma
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More Follicular LymphomaG
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More GGastric Cancer
Afinitor Promising in Treatment of Advanced Gastric Cancer (July 23, 2010)
Afinitor® (everolimus) may be a promising treatment option for patients with metastatic gastric cancer who have undergone previous treatment, according to a study published in the Journal of Clinical Oncology. Afinitor is an oral targeted therapy that... Continue Reading
Clinical Trial for Advanced Gastric Cancer Now Enrolling Patients (July 16, 2010)Gastric cancer forms in the tissues and lining of the stomach. Current treatment options include surgery, chemotherapy, and radiation. The current standard of care for metastatic gastric cancer is systemic therapy. Research is ongoing to determine which... Continue Reading
High Circulating Vitamin D Levels Don’t Reduce Risk of Less Common Cancers (July 13, 2010)High levels of vitamin D in the bloodstream do not appear to reduce the risk of seven less common cancers: endometrial, esophageal, stomach, ovarian, pancreatic, kidney, and non-Hodgkin’s lymphoma. In fact, there was a suggestion that people with the... Continue Reading
Depression May Persist With Metastatic Cancer (May 27, 2010)A substantial number of patients with metastatic cancer may suffer from depression which tends to persist and grow more severe toward the end of life, according to the results of a study published early online in the Journal of Clinical Oncology.[1] While... Continue Reading
Genetic Variant Associated with Poor Outcome for Gastric Cancer (May 24, 2010)Patients with gastric cancer who have a certain type of inherited variation in the CD44 gene experience a significantly shorter time to disease recurrence (2.1 years) compared with patients without the genetic variation (seven years), according to the... Continue Reading
More Gastric CancerGene Therapy
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More Gene TherapyGeneral
Experts Agree that Action is Needed to Address Cancer Care in Poorer Countries (September 8, 2010)
The Global Task Force on Expanded Access to Cancer Care and Control in Developing Countries (GTF.CCC), made up of global health and oncology experts, works toward developing and implementing strategies to provide poorer countries with cancer prevention... Continue Reading
Long-term Cardiac Risks Among Childhood Cancer Survivors (August 5, 2010)Twenty-seven percent of survivors of childhood cancers may have long-term heart complications, according to findings reported in the Archives of Internal Medicine. The survival rate for childhood cancer is high, with 80% of children and adolescents surviving... Continue Reading
Study Evaluates Long-term Side Effects of Pelvic Radiation to Treat Childhood Cancer (August 2, 2010)The offspring of women who underwent pelvic radiation before puberty for the treatment of childhood cancer are at increased risk of stillbirth and neonatal death. These findings were recently published in the journal The Lancet.[1] The survival rate for... Continue Reading
Neoadjuvant Chemotherapy Regimen Promising for Metastatic Penile Cancer (July 28, 2010)A neoadjuvant (before surgery) combination of Taxol® (paclitaxel), Ifex® (ifosfamide), and Platinol® (cisplatin) produced clinically significant responses in patients with bulky regional lymph node metastases from penile cancer, according to the results... Continue Reading
Childhood Cancer Survivors Experience Elevated Risk of Premature Death Years after Diagnosis (July 27, 2010)Childhood cancer survivors may experience a persistently higher risk of premature death due to disease compared with the general population. These findings were recently published in the Journal of the American Medical Association.[1] The survival rate... Continue Reading
More GeneralGeneral Bone Cancer
Denosumab Active Against Giant Cell Tumor of Bone (February 11, 2010)
In a Phase II clinical trial, denosumab produced high rates of tumor response among patients with recurrent or unresectable giant cell tumors of bone. These results were published in Lancet Oncology. Denosumab is an investigational drug that targets... Continue Reading
Denosumab Produces Promising Results Against Giant Cell Tumor of the Bone (June 5, 2009)Denosumab Produces Promising Results Against Giant Cell Tumor of the Bone In a Phase II clinical trial, 86% of patients with giant cell tumor of the bone responded to treatment with the investigational targeted therapy denosumab. These results were presented... Continue Reading
Denosumab Reduces the Risk of Bone Fractures (March 8, 2009)Denosumab Reduces the Risk of Bone Fractures According to the results of a Phase III clinical trial, treatment with denosumab significantly reduces the risk of vertebral and hip fractures among postmenopausal women with osteoporosis. These results were... Continue Reading
More General Bone CancerGeneral Brain Cancer
Cell Phone Towers and Childhood Cancer Risk (July 1, 2010)
Recent findings indicate that children who are exposed to radiofrequency fields from cell phone towers before birth do not have an increased risk of early childhood cancer. This study was published in the British Medical Journal. The health effects—notably,... Continue Reading
Novel Approach Shows Promise for Glioblastoma (June 16, 2010)A new non-invasive treatment has shown promising results in patients with recurrent glioblastoma when compared with the best standard chemotherapy regimens, according to the results of a Phase III study presented at the 2010 annual meeting of the American... Continue Reading
Rindopepimut with Temodar Appears Promising in Newly Diagnosed Glioblastoma Multiforme (June 14, 2010)Maintenance therapy with rindopepimut (CDX-110) combined with Temodar® (temozolomide) resulted in a 70% progression-free rate at 5.5 months for newly diagnosed patients with glioblastoma multiforme (GBM). These findings were recently presented at the... Continue Reading
Recurrent High-grade Glioma Patients May Benefit from Hypofractionated Stereotactic Radiation Therapy (June 1, 2010)Patients with recurrent, high-grade glioma who were treated with hypofractionated stereotactic radiation therapy (H-SRT) experienced minimal side effects and a median survival of 11 months. These results were recently published in the Journal of Clinical... Continue Reading
Optimal Outcomes with Vascular Endothelial Growth Factor (VEGF) Inhibitors Require Appropriate Hypertension Assessment, Monitoring, and Management (May 28, 2010)An expert panel provided consensus recommendations for appropriate prevention, surveillance and treatment of hypertension (high blood pressure) in patients treated with vascular endothelial growth factor (VEGF) signaling pathway inhibitors. These recommendations... Continue Reading
More General Brain CancerGeneral Complementary Alternative Medicine
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More General Complementary Alternative MedicineGeneral Gene Therapy
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More General Gene TherapyGeneral Head and Neck Cancer
Study Evaluates Incidence of Lymphedema Resulting from Cancer Treatment (August 9, 2010)
A systematic review of 47 studies evaluating treatment for melanoma, head and neck cancer, genitourinary cancers, gynecologic cancers, and sarcoma indicates that lymphedema is a common side effect of treatment for these diseases. These findings were recently... Continue Reading
Mixed Findings on Combination Therapy for Nasopharyngeal Cancer (July 26, 2010)Results of a Phase III trial indicate that treating nasopharyngeal cancer with a combination of radiation and chemotherapy can significantly reduce disease progression but that the combination may also increase the rate of death from other causes. These... Continue Reading
Coffee May Reduce Head and Neck Cancer Risk (June 24, 2010)Drinking caffeinated coffee may reduce the risk of cancers of the oral cavity (mouth) and pharynx. These results were published in Cancer Epidemiology, Biomarkers, and Prevention. Head and neck cancers originate in the tissues in or around the mouth,... Continue Reading
Computed Tomography (CT) Has Limitations in Laryngeal Cancer (May 17, 2010)Computed tomography (CT) scans cannot always determine whether laryngeal cancer has penetrated thyroid cartilage or spread beyond the larynx, suggesting that better methods of pretreatment assessment are needed. These results were recently published in... Continue Reading
Accelerated Radiation Schedule May Improve Head and Neck Cancer Outcomes (April 23, 2010)An international study of patients with squamous cell carcinoma of the larynx, pharynx, or oral cavity reported that an accelerated schedule of radiation therapy improved cancer control and was feasible even in low-resource settings. These results... Continue Reading
More General Head and Neck CancerGeneral HIV Related Cancers
Study Evaluates Impact of Highly Active Antiretroviral Therapy (HAART) on Cancer Risk in HIV-infected Men (August 10, 2010)
Researchers reported that men infected with human immunodeficiency virus (HIV) are still at an increased risk of lymphoma, Kaposi’s sarcoma (KS), and anal cancer despite the introduction of highly active antiretroviral therapy (HAART). These findings... Continue Reading
More General HIV Related CancersGeneral Lung Cancer
Vitamin B6 Associated with Lower Risk of Lung Cancer (June 28, 2010)
Individuals with high blood levels of vitamin B6 may be less likely to develop lung cancer compared with their counterparts with lower vitamin B6 levels, according to the results of a study published in the Journal of the American Medical Association.[1] Lung... Continue Reading
Some Blood Pressure Drugs May Raise Cancer Risk (June 23, 2010)It appears that angiotensin-receptor blockers (ARBs), a widely used class of blood pressure drugs, may slightly increase the risk of cancer. These findings were published in the Lancet Oncology. Angiotensin-receptor blockers work by blocking angiotensin... Continue Reading
Lung Cancer Risk and Traffic-related Air Pollution (May 20, 2010)Researchers report a modest association between air pollution resulting from traffic and risk of lung cancer. These findings were recently published in the journal Cancer Epidemiology, Biomarkers & Prevention.[1] Although the relationship between... Continue Reading
Most Survivors of Lung and Colorectal Cancer Keep Their Jobs (April 14, 2010)Among people diagnosed with nonmetastatic lung or colorectal cancer, the majority return to work, according to a study recently published in Journal of Clinical Oncology. Those who do leave the workforce tend to have worse prognoses and lower socioeconomic... Continue Reading
Smoking Cessation After Lung Cancer Diagnosis Improves Survival (February 11, 2010)Quitting smoking after a diagnosis of early-stage lung cancer may reduce the risk of cancer recurrence and death. These results were published in the British Medical Journal. Lung cancer is the leading cause of cancer death in the United States, with... Continue Reading
More General Lung CancerGeneral Malignant Mesothelioma
MVP Does Not Provide Benefit in Mesothelioma Patients (May 21, 2008)
MVP Does Not Provide Benefit in Mesothelioma Patients The chemotherapy agent Navelbine® (vinorelbine) may improve outcomes for patients with malignant pleural mesothelioma. However, the combination chemotherapy regimen referred to as MVP (mitoxantrone,... Continue Reading
Minimally Invasive Endoscopic Procedure Shows Promise for Detecting Lung Cancer (February 8, 2008)Minimally Invasive Endoscopic Procedure Shows Promise for Detecting Lung Cancer Use of a minimally invasive technique called endoscopy to detect lung cancer may be more effective than more complicated and invasive standard procedures. These findings were... Continue Reading
More General Malignant MesotheliomaGeneral Myelodysplastic Syndrome
Vidaza® Improves Survival in Higher-risk Myelodysplastic Syndromes (March 6, 2009)
According to the results of a Phase III clinical trial, treatment with Vidaza® (azacitidine) results in better survival than conventional care among patients with higher-risk myelodysplastic syndromes (MDS). These results were published in Lancet Oncology. Myelodysplastic... Continue Reading
The American Society of Clinical Oncology 2008: Highlights of Treatment of Hematological Malignancies (January 30, 2009)The American Society of Clinical Oncology 2008: Highlights of Treatment of Hematological Malignancies The 2008 annual meeting of the American Society of Clinical Oncology (ASCO), held in Chicago, Illinois, again revealed advances in the treatment of... Continue Reading
New Risk Model for MDS Applies to All Stages of Disease (December 31, 2008)New Risk Model for MDS Applies to All Stages of Disease A new risk model for myelodysplastic syndrome (MDS) provides survival projections for all stages of the disease and has proven superior to the International Prognostic Scoring System (IPSS) that... Continue Reading
Older Age Does Not Affect Survival in Patients with AML or MDS Who Undergo Mini-transplants (December 30, 2008)Older Age Does Not Affect Survival in Patients with AML or MDS Who Undergo Mini-transplants Age should not be a barrier for non-myeloablative allogeneic stem cell transplantation in patients with acute myeloid leukemia (AML) or myelodysplastic syndrome... Continue Reading
Vidaza® Approved for High-risk MDS (August 22, 2008)Vidaza® Approved for High-risk MDS The US Food and Drug Administration (FDA) has approved Vidaza® (azacitadine) for the treatment of high-risk myelodysplastic syndromes. Vidaza is already approved for MDS that is categorized into all five French American... Continue Reading
More General Myelodysplastic SyndromeGeneral Neuroblastoma
Neuroblastoma Survival has Improved (May 11, 2010)
Between 1979 and 2005, ten-year overall survival with neuroblastoma improved from 34.9% to 65%. The results of this study, conducted in Italy, were published in the Journal of Clinical Oncology. Neuroblastoma is a disease in which cancerous cells form... Continue Reading
Genetic Variation Associated with Risk of Neuroblastoma (March 8, 2009)Genetic Variation Associated with Risk of Neuroblastoma Individuals with a common genetic variation (change in DNA) on the chromosome band 6p22 have a significantly increased risk of developing neuroblastoma, as well as an increased risk for disease relapse... Continue Reading
More General NeuroblastomaGeneral Renal Cancer
High Circulating Vitamin D Levels Don’t Reduce Risk of Less Common Cancers (July 13, 2010)
High levels of vitamin D in the bloodstream do not appear to reduce the risk of seven less common cancers: endometrial, esophageal, stomach, ovarian, pancreatic, kidney, and non-Hodgkin’s lymphoma. In fact, there was a suggestion that people with the... Continue Reading
Optimal Outcomes with Vascular Endothelial Growth Factor (VEGF) Inhibitors Require Appropriate Hypertension Assessment, Monitoring, and Management (May 28, 2010)An expert panel provided consensus recommendations for appropriate prevention, surveillance and treatment of hypertension (high blood pressure) in patients treated with vascular endothelial growth factor (VEGF) signaling pathway inhibitors. These recommendations... Continue Reading
Chronic Hepatitis C Infection May Increase Risk for Developing Renal Cell Carcinoma (April 22, 2010)Chronic infection with hepatitis C virus may increase the risk of renal cell cancer (RCC), according to results published in the journal Cancer Epidemiology, Biomarkers and Prevention.[1] The kidneys are filled with tiny tubules that clean and filter... Continue Reading
Radiofrequency Ablation Effective For Small Kidney Cancers (March 12, 2010)Radiofrequency ablation appears to be an effective treatment for patients with small kidney cancers. These results were presented at the 2010 ASCO Genitourinary Cancers Symposium. The kidneys are each filled with tiny tubules that clean and filter ... Continue Reading
Cryoablation Effective for Renal Cancer (March 4, 2010)Stereotactic percutaneous cryoablation and laparoscopic renal cryoablation are effective treatments for selected patients with kidney cancer, according to the results of two studies published in the Journal of Urology.1,2 The kidneys are each filled... Continue Reading
More General Renal CancerGeneral Retinoblastoma
Retinoblastoma Survivors Face Risk of Second Cancers (March 8, 2009)
Retinoblastoma Survivors Face Risk of Second Cancers A study that followed retinoblastoma survivors for up to 61 years reported a high risk of second cancers among survivors of hereditary retinoblastoma. These results were published in the Journal of... Continue Reading
Chemotherapy for Retinoblastoma Delivered Directly into Eye May Save Eye (March 8, 2009)Chemotherapy for Retinoblastoma Delivered Directly into Eye May Save Eye Chemotherapy delivered directly into the artery of the eye may save the eyeball in children with retinoblastoma. These results were recently published in an early online publication... Continue Reading
More General RetinoblastomaGeneral Sarcoma
High-risk Soft Tissue Sarcoma Patients Benefit from Targeted Heat Therapy Combined with Chemotherapy (May 7, 2010)
A technique called regional hyperthermia (RHT) makes chemotherapy more effective and improves outcomes in patients with localized, high-risk soft tissue sarcoma, according to the results of a study recently published in the journal The Lancet.[1] These... Continue Reading
Targeted Heat Therapy Improves Outcomes for Soft Tissue Sarcoma (September 30, 2009)A new technique called regional hyperthermia (RHT) makes chemotherapy more effective and improves outcomes in patients with soft tissue sarcoma, according to the results of a study presented on September 22, 2009 at Europe’s largest cancer congress,... Continue Reading
Gleevec® Approved for Adjuvant Treatment of Gastrointestinal Stromal Tumors (March 8, 2009)Gleevec® Approved for Adjuvant Treatment of Gastrointestinal Stromal Tumors The U.S. Food and Drug Administration has expanded the approval of Gleevec® (imatinib mesylate) to include the adjuvant (post-surgery) treatment of Kit-positive gastrointestinal... Continue Reading
Differences in IMRT Radiation Doses May Complicate Study Results in Sarcomas (March 8, 2009)Differences in IMRT Radiation Doses May Complicate Study Results in Sarcomas Differences between the prescribed dose of radiation in intensity modulated radiation therapy (IMRT) and the dose that’s actually delivered may make comparison studies... Continue Reading
PET Scan More Accurate Predictor of Treatment Response for Soft Tissue Sarcomas (March 8, 2009)PET Scan More Accurate Predictor of Treatment Response for Soft Tissue Sarcomas Positron emission tomography (PET) scans were found to be significantly more accurate than standard methods in judging response to first-line treatment for high-grade soft... Continue Reading
More General SarcomaGeneral Skin Cancer
HPV Infection May Raise Skin Cancer Risk (July 13, 2010)
It appears that infection with certain types of human papillomavirus (HPV) may be linked with the incidence of squamous cell carcinoma, a form of skin cancer. These findings were recently published in the journal BMJ. There are three main types of cancers... Continue Reading
Indoor Tanning May Be Addictive in Some Individuals (April 29, 2010)Researchers report that some individuals may meet criteria for addiction to indoor tanning and are more likely to exhibit other addictive behaviors and affective disturbance. These results were recently published in the journal Archives of Dermatology.[1] Each... Continue Reading
Tanning Beds Classified as “Carcinogenic to Humans” (July 29, 2009)The International Agency for Research on Cancer (IARC) now classifies tanning beds and other UV-emitting tanning devices as Group 1 carcinogens, meaning that there is sufficient evidence to conclude that these devices cause cancer in humans.[1] Use of... Continue Reading
Moh’s Micrographic Surgery More Effective than Excision for Recurrent Basal Cell Carcinoma of the Face (March 8, 2009)Moh’s Micrographic Surgery More Effective than Excision for Recurrent Basal Cell Carcinoma of the Face Moh’s micrographic surgery (MMS) for the treatment of recurrent basal cell carcinoma (rBCC) of the face results in fewer recurrences than... Continue Reading
Non-melanoma Skin Cancer Associated with Increased Risk of Other Cancers (March 8, 2009)Non-melanoma Skin Cancer Associated with Increased Risk of Other Cancers Individuals who have been diagnosed with squamous cell or basal cell carcinoma have an increased risk of developing subsequent cancers other than skin cancer. These results were... Continue Reading
More General Skin CancerGeneral Thyroid Cancer
Vandetanib Delays Progression of Advanced Medullary Thyroid Cancer (July 16, 2010)
Results of a Phase III clinical trial indicate that the investigational drug vandetanib delays the progression of locally advanced or metastatic medullary thyroid cancer. These results were presented at the 2010 annual meeting of the American Society... Continue Reading
Childhood Cancer Survivors at Risk for Thyroid Cancer (November 2, 2009)Survivors of childhood cancer are 18 times more likely to develop thyroid cancer than the general population, according to the results of a study published in the International Journal of Cancer.[1] Survivors of childhood cancers are often at risk for... Continue Reading
Thyroid Cancer: It’s Not in Your Head-It’s in Your Neck! (March 8, 2009)Thyroid Cancer: It’s Not in Your Head-It’s in Your Neck! A thyroid cancer survivor shares valuable information about the disease and insight into the treatment process. It all started with bumps-what I would later learn were actually called... Continue Reading
Nexavar® Provides Anticancer Activity in Advanced Thyroid Cancer (March 8, 2009)Nexavar® Provides Anticancer Activity in Advanced Thyroid Cancer Nexavar® (sorafenib) provides cancer control among patients with thyroid cancer that has progressed following standard therapy. These results were recently published in the Journal of... Continue Reading
Motesanib Diphosphate Provides Anticancer Activity Among Patients with Progressive Thyroid Cancer (March 8, 2009)Motesanib Diphosphate Provides Anticancer Activity Among Patients with Progressive Thyroid Cancer The investigative agent motesanib diphosphate (AMG 706) produces a regression of cancer among patients with thyroid cancer that is progressing despite... Continue Reading
More General Thyroid CancerGeneral Vaginal Cancer
Tumor Burden in Sentinel Node May Help Stratify High- and Low-risk Vulvar Cancer Patients (June 15, 2010)
Tumor burden in the sentinel node of early-stage vulvar cancer patients appears to be an important prognostic factor. Patients with sentinel-node metastasis larger than 2mm may have a worse prognosis. These findings were recently published in the journal... Continue Reading
Gardasil® Approved for Prevention of Vaginal and Vulvar Cancers (March 8, 2009)Gardasil® Approved for Prevention of Vaginal and Vulvar Cancers The United States Food and Drug Administration (FDA) has expanded the indication for Gardasil® (Quadrivalent Human Papillomavirus [Types 6, 11, 16, 18] Recombinant Vaccine) for the prevention... Continue Reading
Updates in the Management of Gynecologic Cancers (May 27, 2008)Updates in the Management of Gynecologic Cancers: A Report from the 39th Annual Meeting of the Society of Gynecologic Oncologists The 39th Annual Meeting of the Society of Gynecologic Oncologists (SGO) was held in Tampa, Florida, from March 9 to 12, 2008,... Continue Reading
Aldara™ Effective Alternative to Surgery for Precancerous Changes to Vulva (April 11, 2008)Aldara™ Effective Alternative to Surgery for Precancerous Changes to Vulva A recently published study in the New England Journal of Medicine reports that topical Aldara™ (imiquimod) may be an effective alternative to surgery for the treatment of precancerous... Continue Reading
More General Vaginal CancerH
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More HHairy Cell Leukemia
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More Hairy Cell LeukemiaHead and Neck Cancer
Study Evaluates Incidence of Lymphedema Resulting from Cancer Treatment (August 9, 2010)
A systematic review of 47 studies evaluating treatment for melanoma, head and neck cancer, genitourinary cancers, gynecologic cancers, and sarcoma indicates that lymphedema is a common side effect of treatment for these diseases. These findings were recently... Continue Reading
Mixed Findings on Combination Therapy for Nasopharyngeal Cancer (July 26, 2010)Results of a Phase III trial indicate that treating nasopharyngeal cancer with a combination of radiation and chemotherapy can significantly reduce disease progression but that the combination may also increase the rate of death from other causes. These... Continue Reading
Coffee May Reduce Head and Neck Cancer Risk (June 24, 2010)Drinking caffeinated coffee may reduce the risk of cancers of the oral cavity (mouth) and pharynx. These results were published in Cancer Epidemiology, Biomarkers, and Prevention. Head and neck cancers originate in the tissues in or around the mouth,... Continue Reading
Computed Tomography (CT) Has Limitations in Laryngeal Cancer (May 17, 2010)Computed tomography (CT) scans cannot always determine whether laryngeal cancer has penetrated thyroid cartilage or spread beyond the larynx, suggesting that better methods of pretreatment assessment are needed. These results were recently published in... Continue Reading
Accelerated Radiation Schedule May Improve Head and Neck Cancer Outcomes (April 23, 2010)An international study of patients with squamous cell carcinoma of the larynx, pharynx, or oral cavity reported that an accelerated schedule of radiation therapy improved cancer control and was feasible even in low-resource settings. These results... Continue Reading
More Head and Neck CancerHepatocellular Carcinoma Liver Cancer
Sutent® Not Effective for Advanced Liver Cancer (July 10, 2009)
In a Phase II clinical trial, patients with inoperable, advanced hepatocellular (liver) cancer did not benefit from treatment with the targeted therapy Sutent® (sunitinib). The results of this study were published in Lancet Oncology. Hepatocellular carcinoma... Continue Reading
Women with Hypothyroidism at Increased Risk of Liver Cancer (June 22, 2009)Women with Hypothyroidism at Increased Risk of Liver Cancer Long-term hypothyroidism in women significantly increases the risk of developing hepatocellular carcinoma (liver cancer), according to the results of a study published in Hepatology.[1] The liver... Continue Reading
Genetic Characteristics of Hepatitis B Associated with Risk of Liver Cancer (March 8, 2009)Genetic Characteristics of Hepatitis B Associated with Risk of Liver Cancer Different genetic characteristics of the hepatitis B virus (HBV) are associated with varying risks of developing hepatocellular carcinoma (HCC), the most common form of liver... Continue Reading
Nexavar® Improves Survival in Advanced Liver Cancer (March 8, 2009)Nexavar® Improves Survival in Advanced Liver Cancer The targeted agent Nexavar (sorafenib) is associated with improved survival and doubling of the time to cancer progression for patients with advanced liver cancer. These results were recently published... Continue Reading
Liver Cancer Screening in Patients with Chronic Hepatitis B and C Improves Survival (March 8, 2009)Liver Cancer Screening in Patients with Chronic Hepatitis B and C Improves Survival Researchers in Hong Kong have reported that screening patients with chronic hepatitis for liver cancer improves liver cancer survival rates and may improve chances for... Continue Reading
More Hepatocellular Carcinoma Liver CancerHighly Aggressive/High Grade Non-Hodgkin's Lymphoma
Survivors of Some Childhood Cancers May Face Cognitive Impairment (May 18, 2010)
Survivors of non-central nervous system (CNS) childhood cancers reported a statistically and clinically significantly higher rate of neurocognitive impairment than their cancer-free siblings, according to the results of a study published in the Journal... Continue Reading
Children and Teens Have Better NHL Survival than Young Adults (March 15, 2010)Even after accounting for stage at diagnosis and subtype of non-Hodgkin’s lymphoma (NHL), children and teens with NHL have better survival than young adults with NHL. These results were published in the Archives of Pediatrics and Adolescent Medicine. Non-Hodgkin’s... Continue Reading
New and Novel Agents for the Treatment of Non-Hodgkin’s Lymphoma: A Report from the 2008 Meeting of the American Society of Hematology (March 8, 2009)New and Novel Agents for the Treatment of Non-Hodgkin’s Lymphoma: A Report from the 2008 Meeting of the American Society of Hematology The 2008 ASH meeting featured several reports of new agents that are showing promise in the treatment of Non-Hodgkin’s... Continue Reading
Smoking and Heavy Alcohol Consumption Reduce Survival in Non-Hodgkin’s Lymphoma (March 8, 2009)Smoking and Heavy Alcohol Consumption Reduce Survival in Non-Hodgkin’s Lymphoma Patients diagnosed with non-Hodgkin’s lymphoma (NHL) who smoke tobacco products and/or drink large quantities of alcohol have a reduced chance of optimal survival.... Continue Reading
Statins May Reduce Effectiveness of Rituxan® in Non-Hodgkin’s Lymphoma (March 8, 2009)Statins May Reduce Effectiveness of Rituxan® in Non-Hodgkin’s Lymphoma Statins may reduce the effectiveness of Rituxan® (rituximab) in treatment of non-Hodgkin’s lymphoma (NHL), according to a recently published article in PLoS Med (the... Continue Reading
More Highly Aggressive/High Grade Non-Hodgkin's LymphomaHIV Related Cancers
Study Evaluates Impact of Highly Active Antiretroviral Therapy (HAART) on Cancer Risk in HIV-infected Men (August 10, 2010)
Researchers reported that men infected with human immunodeficiency virus (HIV) are still at an increased risk of lymphoma, Kaposi’s sarcoma (KS), and anal cancer despite the introduction of highly active antiretroviral therapy (HAART). These findings... Continue Reading
Immunosuppression Increases Risk of HPV-related Cancers in AIDS Patients (August 20, 2009)The risk of HPV-related cancers is elevated among AIDS patients. This risk continues to increase as patients’ immune systems become more compromised, according to the results of a study published in the Journal of the National Cancer Institute.[1] Human... Continue Reading
More HIV Related CancersHodgkin's Lymphoma
Reduced-intensity Treatment May be Effective for Early Hodgkin’s Lymphoma (August 27, 2010)
Among patients with early-stage Hodgkin’s lymphoma and a favorable prognosis, it may be possible to reduce the number of chemotherapy cycles and the dose of radiation therapy without adversely affecting outcome. The results of this study were published... Continue Reading
Study Confirms that Radiation Therapy Is Not Necessary in Patients with Favorable, Limited-stage Hodgkin’s Lymphoma (April 5, 2010)Researchers from the Dana-Farber Cancer Center have confirmed prior studies that indicate chemotherapy alone is safe and effective for the treatment of early-stage Hodgkin’s Lymphoma in appropriate patients. The details of this study were published... Continue Reading
Childhood Cancer Survivors Treated with Radiation Therapy at Increased Risk of Death from Heart Disease in Adulthood (March 26, 2010)A dose of as little as 5 Gy of radiation therapy to the heart for the treatment of childhood cancers results in a significant increase in cardiac death later in life, according to a study recently published in the Journal of Clinical Oncology.[1] Survivors... Continue Reading
Allogeneic Stem Cell Transplantation Viable for Children and Adolescents with Relapsed Hodgkin’s Lymphoma (September 24, 2009)Children and adolescents with relapsed Hodgkin’s lymphoma respond well to allogeneic stem cell transplantation, according to the results of a study published in Blood.[1] Although children and adolescents with Hodgkin’s lymphoma have an excellent... Continue Reading
Hodgkin’s Survivors at Increased Risk of Stroke (June 24, 2009)Hodgkin’s Survivors at Increased Risk of Stroke Patients who have been treated with radiation therapy for Hodgkin’s lymphoma have an elevated risk of stroke. These results were published in the Journal of the National Cancer Institute. Hodgkin’s... Continue Reading
More Hodgkin's LymphomaHormonal Therapy
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More Hormonal TherapyI
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More IIndolent/Low Grade Non-Hodgkin's Lymphoma
Maintenance Therapy with Rituxan Prolongs Lymphoma Remission (May 26, 2010)
Among patients with follicular lymphoma who responded to initial treatment with chemotherapy and Rituxan® (rituximab), those who received an additional two years of Rituxan as maintenance therapy remained free of lymphoma progression for longer than... Continue Reading
Survivors of Some Childhood Cancers May Face Cognitive Impairment (May 18, 2010)Survivors of non-central nervous system (CNS) childhood cancers reported a statistically and clinically significantly higher rate of neurocognitive impairment than their cancer-free siblings, according to the results of a study published in the Journal... Continue Reading
Children and Teens Have Better NHL Survival than Young Adults (March 15, 2010)Even after accounting for stage at diagnosis and subtype of non-Hodgkin’s lymphoma (NHL), children and teens with NHL have better survival than young adults with NHL. These results were published in the Archives of Pediatrics and Adolescent Medicine. Non-Hodgkin’s... Continue Reading
Idiotype Vaccine Improves Disease-free Survival in Patients with Follicular Lymphoma (June 8, 2009)Idiotype Vaccine Improves Disease-free Survival in Patients with Follicular Lymphoma BiovaxID, an individualized tumor-specific protein vaccine, prolongs disease-free survival in patients with advanced follicular lymphoma who experience complete remission... Continue Reading
New and Novel Agents for the Treatment of Non-Hodgkin’s Lymphoma: A Report from the 2008 Meeting of the American Society of Hematology (March 8, 2009)New and Novel Agents for the Treatment of Non-Hodgkin’s Lymphoma: A Report from the 2008 Meeting of the American Society of Hematology The 2008 ASH meeting featured several reports of new agents that are showing promise in the treatment of Non-Hodgkin’s... Continue Reading
More Indolent/Low Grade Non-Hodgkin's LymphomaInflammatory Breast Cancer
Racial Disparity in Breast Cancer Outcomes Among Underinsured (June 30, 2010)
Underinsured African-Americans have worse breast cancer survival outcomes than their underinsured White counterparts, according to the results of a study published early online in the Journal of the National Caner Institute.[i] The disparity in breast... Continue Reading
Tykerb plus Taxol Is Active in Inflammatory Breast Cancer (June 17, 2010)Tykerb® (lapatinib) plus Taxol® (paclitaxel) appears to provide benefit in the initial treatment of inflammatory breast cancer, according to results published in the Journal of Clinical Oncology. Inflammatory breast cancer (IBC) is the most aggressive... Continue Reading
Lifestyle Factors Increase Risk of Second Breast Cancer (September 24, 2009)Obesity, alcohol consumption, and smoking significantly increase the risk of second breast cancers among breast cancer survivors, according to the results of a study published in the Journal of Clinical Oncology.[1] Approximately 200,000 women are diagnosed... Continue Reading
FDA Approves New Test to Detect HER2 Status in Breast Cancer (March 8, 2009)FDA Approves New Test to Detect HER2 Status in Breast Cancer The U.S. Food and Drug Administration (FDA) has approved a new laboratory test to help identify patients with breast cancer who may benefit from treatment with Herceptin® (trastuzumab). The... Continue Reading
Specific Gene Mutations May Affect Response to Tamoxifen in Breast Cancer (March 8, 2009)Specific Gene Mutations May Affect Response to Tamoxifen in Breast Cancer Mutations within the CYP2D6 gene may affect the way in which a patient with hormone-positive breast cancer responds to tamoxifen (Nolvadex®). These results were recently published... Continue Reading
More Inflammatory Breast CancerInfo Type
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More Info TypeJ
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More JK
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More LLeukemia
Newly Diagnosed Ph+ Acute Lymphoblastic Leukemia Patients May Benefit from Sprycel/Chemotherapy Combination (July 28, 2010)
The initial report of a Phase II study evaluating Sprycel® (dasatinib) combined with chemotherapy for the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) indicates that 94% of patients achieve a complete remission.... Continue Reading
Cell Phone Towers and Childhood Cancer Risk (July 1, 2010)Recent findings indicate that children who are exposed to radiofrequency fields from cell phone towers before birth do not have an increased risk of early childhood cancer. This study was published in the British Medical Journal. The health effects—notably,... Continue Reading
Mylotarg Withdrawn from Market in United States (June 23, 2010)Mylotarg® (gemtuzumab ozogamicin), a drug used for the treatment of acute myeloid leukemia (AML), will be withdrawn from the U.S. market following a recent clinical trial that raised new concerns about safety and failed to demonstrate clinical benefit. Mylotarg... Continue Reading
Tasigna Approved for Initial Treatment of Chronic Myeloid Leukemia (June 22, 2010)The U.S. Food and Drug Administration has expanded the approval of Tasigna® (nilotinib) to include the initial treatment of patients with Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase. Each year in the United States, approximately... Continue Reading
Sprycel May Be More Effective than Gleevec for Initial Treatment of CML (June 7, 2010)In the initial treatment of chronic myeloid leukemia (CML), Sprycel® (dasatinib) produces higher response rates than Gleevec® (imatinib). These results were presented at the 2010 annual meeting of the American Society of Clinical Oncology. Each year... Continue Reading
More LeukemiaLimited Disease Lung Cancer - Small Cell
Most Survivors of Lung and Colorectal Cancer Keep Their Jobs (April 14, 2010)
Among people diagnosed with nonmetastatic lung or colorectal cancer, the majority return to work, according to a study recently published in Journal of Clinical Oncology. Those who do leave the workforce tend to have worse prognoses and lower socioeconomic... Continue Reading
Smoking Cessation After Lung Cancer Diagnosis Improves Survival (February 11, 2010)Quitting smoking after a diagnosis of early-stage lung cancer may reduce the risk of cancer recurrence and death. These results were published in the British Medical Journal. Lung cancer is the leading cause of cancer death in the United States, with... Continue Reading
November Is National Lung Cancer Awareness Month (November 6, 2009)As the month of November brings lung cancer into focus, it’s time to increase public understanding of the disease, including its prevalence, approaches to screening and prevention, treatment options, and resources that offer updated lung cancer information... Continue Reading
Thalidomide Doesn’t Benefit Patients with Small Cell Lung Cancer (July 22, 2009)Treatment with a combination of thalidomide and chemotherapy did not improve survival among patients with small cell lung cancer, and resulted in a higher risk of blood clots than treatment with chemotherapy alone. The results of this study were published... Continue Reading
Higher Chemotherapy Dose Intensity Does Not Improve Survival for Small Cell Lung Cancer (March 8, 2009)Higher Chemotherapy Dose Intensity Does Not Improve Survival for Small Cell Lung Cancer Increasing the dose intensity of chemotherapy does not appear to improve survival in small cell lung cancer. These results were recently published in the Journal of... Continue Reading
More Limited Disease Lung Cancer - Small CellLiver Cancer
Liver Cancer Incidence is on the Rise in the United States (May 25, 2010)
From 2001 to 2006, the incidence of hepatocellular carcinoma (HCC) increased significantly with an average increase of 3.5% annually. This analysis was recently reported in the Centers for Disease Control and Prevention’s (CDC) Morbidity and Mortality... Continue Reading
Combination Chemotherapy Improves Survival with Biliary Tract Cancer (May 17, 2010)According to the results of a Phase III clinical trial, treatment of locally advanced or metastatic biliary tract cancer with a combination of Gemzar® (gemcitabine) and cisplatin results in better survival and a lower risk of cancer progression than... Continue Reading
Liver Cancer Often Linked to Diabetes (May 4, 2010)Diabetes increases the risk of hepatocellular carcinoma (HCC) and may account for a greater number of HCC cases in the United States than any other single HCC risk factor. These results were presented at the 101st annual meeting of the American Association... Continue Reading
Women with Hypothyroidism at Increased Risk of Liver Cancer (June 22, 2009)Women with Hypothyroidism at Increased Risk of Liver Cancer Long-term hypothyroidism in women significantly increases the risk of developing hepatocellular carcinoma (liver cancer), according to the results of a study published in Hepatology.[1] The liver... Continue Reading
Incidence of Liver Cancer on the Rise (April 8, 2009)The incidence of liver cancer in the United States tripled between 1975 and 2005, but survival rates are improving, according to the results of a study published in the Journal of Clinical Oncology. The liver is the largest organ in the body and is responsible... Continue Reading
More Liver CancerLocally Advanced Stage III (C) Prostate Cancer
Study Evaluates Incidence of Lymphedema Resulting from Cancer Treatment (August 9, 2010)
A systematic review of 47 studies evaluating treatment for melanoma, head and neck cancer, genitourinary cancers, gynecologic cancers, and sarcoma indicates that lymphedema is a common side effect of treatment for these diseases. These findings were recently... Continue Reading
Study Explores Prostate Cancer Among Men with Low PSA Levels (July 30, 2010)In a large U.S. cancer database, 14% of prostate cancer diagnoses occurred among men with a prostate-specific antigen (PSA) level of 4.0 ng/mL or lower. More than half of these men had cancer that was considered “low-risk,” but roughly three-quarters... Continue Reading
Addition of Radiation to Hormone Therapy Improves Survival in Locally Advanced Prostate Cancer (June 8, 2010)The addition of radiation therapy to hormone therapy reduces the risk of prostate cancer death by 43% among men with locally advanced or high-risk prostate cancer compared with hormone therapy alone, according to the results of a phase III study presented... Continue Reading
Prostate Cancer and the Increased Risk of Blood Clots (April 23, 2010)Men with prostate cancer are at a higher risk for several types of thromboembolic diseases (blood clots), with men undergoing endocrine therapy having the highest risk, according to the results of a study published in the Lancet Oncology.[1] In general,... Continue Reading
Neoadjuvant Chemotherapy for High-risk Localized Prostate Cancer Is Safe and Effective (March 19, 2010)Neoadjuvant treatment with Taxotere® (docetaxel) and Emcyt® (estramustine) for high-risk localized prostate cancer appears to be safe and produces promising responses compared with standard treatment, according to the results of a Phase III randomized... Continue Reading
More Locally Advanced Stage III (C) Prostate CancerLung Cancer
Estrogen Alone Does Not Increase Lung Cancer Incidence or Mortality in Postmenopausal Women (August 30, 2010)
Among postmenopausal women, hormone therapy with estrogen alone does not appear to increase the risk of getting or dying from lung cancer. These results were published in the Journal of the National Cancer Institute. As women reach menopause and beyond,... Continue Reading
Vitamin B6 Associated with Lower Risk of Lung Cancer (June 28, 2010)Individuals with high blood levels of vitamin B6 may be less likely to develop lung cancer compared with their counterparts with lower vitamin B6 levels, according to the results of a study published in the Journal of the American Medical Association.[1] Lung... Continue Reading
Some Blood Pressure Drugs May Raise Cancer Risk (June 23, 2010)It appears that angiotensin-receptor blockers (ARBs), a widely used class of blood pressure drugs, may slightly increase the risk of cancer. These findings were published in the Lancet Oncology. Angiotensin-receptor blockers work by blocking angiotensin... Continue Reading
Lung Cancer Risk and Traffic-related Air Pollution (May 20, 2010)Researchers report a modest association between air pollution resulting from traffic and risk of lung cancer. These findings were recently published in the journal Cancer Epidemiology, Biomarkers & Prevention.[1] Although the relationship between... Continue Reading
Most Survivors of Lung and Colorectal Cancer Keep Their Jobs (April 14, 2010)Among people diagnosed with nonmetastatic lung or colorectal cancer, the majority return to work, according to a study recently published in Journal of Clinical Oncology. Those who do leave the workforce tend to have worse prognoses and lower socioeconomic... Continue Reading
More Lung CancerLung Cancer - Non-Small Cell
Addition of Sutent to Tarceva Does Not Improve Overall Survival with Advanced Non-Small Cell Lung Cancer (September 7, 2010)
Among patients with previously treated non-small cell lung cancer, the combination of Sutent® (sunitinib) and Tarceva® (erlotinib) delays cancer progression but does not improve overall survival compared with Tarceva alone. The results of this Phase... Continue Reading
Early Palliative Care Linked with Longer Lung Cancer Survival (September 1, 2010)Palliative care is care that is focused on symptom management, psychosocial issues, decision-making, and quality of life. Among patients with newly diagnosed, metastatic, non-small cell lung cancer, the addition of early palliative care to standard cancer... Continue Reading
Estrogen Alone Does Not Increase Lung Cancer Incidence or Mortality in Postmenopausal Women (August 30, 2010)Among postmenopausal women, hormone therapy with estrogen alone does not appear to increase the risk of getting or dying from lung cancer. These results were published in the Journal of the National Cancer Institute. As women reach menopause and beyond,... Continue Reading
Study Evaluates Safety of Avastin and Chemotherapy in Non–Squamous Non–Small Cell Lung Cancer (August 3, 2010)A large Phase IV study confirms that the safety and efficacy reported in Phase III trials of Avastin® (bevacizumab) plus standard chemotherapy for patients with advanced non-squamous non-small cell lung cancer translate into the clinical practice setting.... Continue Reading
Vitamin B6 Associated with Lower Risk of Lung Cancer (June 28, 2010)Individuals with high blood levels of vitamin B6 may be less likely to develop lung cancer compared with their counterparts with lower vitamin B6 levels, according to the results of a study published in the Journal of the American Medical Association.[1] Lung... Continue Reading
More Lung Cancer - Non-Small CellLung Cancer - Small Cell
Estrogen Alone Does Not Increase Lung Cancer Incidence or Mortality in Postmenopausal Women (August 30, 2010)
Among postmenopausal women, hormone therapy with estrogen alone does not appear to increase the risk of getting or dying from lung cancer. These results were published in the Journal of the National Cancer Institute. As women reach menopause and beyond,... Continue Reading
Vitamin B6 Associated with Lower Risk of Lung Cancer (June 28, 2010)Individuals with high blood levels of vitamin B6 may be less likely to develop lung cancer compared with their counterparts with lower vitamin B6 levels, according to the results of a study published in the Journal of the American Medical Association.[1] Lung... Continue Reading
Some Blood Pressure Drugs May Raise Cancer Risk (June 23, 2010)It appears that angiotensin-receptor blockers (ARBs), a widely used class of blood pressure drugs, may slightly increase the risk of cancer. These findings were published in the Lancet Oncology. Angiotensin-receptor blockers work by blocking angiotensin... Continue Reading
Depression May Persist With Metastatic Cancer (May 27, 2010)A substantial number of patients with metastatic cancer may suffer from depression which tends to persist and grow more severe toward the end of life, according to the results of a study published early online in the Journal of Clinical Oncology.[1] While... Continue Reading
High Rate of False-positive Results in Lung Cancer Screening with CT Scan (April 28, 2010)Screening for lung cancer using computed tomography (CT) scans can yield a high rate of false-positive results, according to a study published in the Annals of Internal Medicine. False-positive results are risky because they may lead to invasive follow-up... Continue Reading
More Lung Cancer - Small CellLymphoma
Intensive Chemotherapy Prolongs Remission of Mantle Cell Lymphoma (December 12, 2008)
Intensive Chemotherapy Prolongs Remission of Mantle Cell Lymphoma In a study of intensive chemotherapy for mantle cell lymphoma, more than half of patients 65 or younger were still in remission after seven years. These results were presented at the 50th... Continue Reading
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More MManagement and Prevention of Anemia Supportive Care
Exercise Reduces Chemotherapy-related Fatigue (October 21, 2009)
Exercise reduces fatigue and improves strength, physical functioning, and emotional well-being in men and women undergoing chemotherapy, according to the results of a study published in the British Medical Journal.[1] While exercise has long been associated... Continue Reading
More Management and Prevention of Anemia Supportive CareManagement and Prevention of Anorexia and Weight Loss Supportive Care
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More Management and Prevention of Anorexia and Weight Loss Supportive CareManagement and Prevention of Bone Complications Supportive Care
Denosumab More Effective Than Zometa in Prostate Cancer Patients with Bone Metastases (February 10, 2010)
Among men with bone metastases from prostate cancer, the investigational drug denosumab was more effective than Zometa® (zoledronic acid) at delaying or preventing bone complications such as fracture. Results from this Phase III clinical trial will... Continue Reading
Bisphosphonates May Provide Breast Cancer Benefits (December 11, 2009)Studies presented at the 2009 San Antonio Breast Cancer Symposium suggest that the class of bone drugs known as bisphosphonates may reduce the risk of breast cancer and may help to maintain bone density in breast cancer patients treated with aromatase... Continue Reading
Denosumab Reduces Bone Complications in Breast Cancer Patients with Bone Metastases (December 10, 2009)Among women with bone metastases from breast cancer, the investigational drug denosumab was more effective than Zometa® (zoledronic acid) at delaying or preventing bone complications such as fracture. The results of this Phase III clinical trial were... Continue Reading
Denosumab Provides Bone Benefits in Advanced Cancer (September 21, 2009)Among patients with bone metastases from cancers other than breast or prostate cancer, denosumab is at least as effective as Zometa® (zoledronic acid) at reducing the risk of bone complications. These results were presented at a major European cancer... Continue Reading
Denosumab Reduces Fractures in Postmenopausal Osteoporosis (August 12, 2009)Denosumab increases bone mineral density (BMD) and reduces the risk of vertebral fractures in women with postmenopausal osteoporosis, according to the results of a study published in the New England Journal of Medicine.[i] Denosumab is an investigational... Continue Reading
More Management and Prevention of Bone Complications Supportive CareManagement and Prevention of Fatigue Supportive Care
Yoga Improves Sleep and Quality of Life (May 26, 2010)
A four-week yoga program that included breathing, meditation, postures, and other techniques improved sleep and quality of life among cancer survivors. The results of this study will be presented at the 2010 annual meeting of the American Society of Clinical... Continue Reading
More Management and Prevention of Fatigue Supportive CareManagement and Prevention of Mucositis Supportive Care
Kepivance Reduces Toxicity of High-dose Therapy for Multiple Myeloma (March 24, 2010)
Among patients undergoing high-dose therapy and autologous stem cell transplantation for multiple myeloma, a three-day short course of Kepivance® (palifermin) reduces the toxicity of treatment. These results were published in the Annals of Oncology. Multiple... Continue Reading
Oral Spray Reduces Mouth Sores (July 21, 2009)Among patients treated with radiation therapy for head and neck cancer, mouth sores (oral mucositis) were reduced by use of an oral spray containing epidermal growth factor (EGF). These results were published in Cancer. Mouth sores are one of the most... Continue Reading
More Management and Prevention of Mucositis Supportive CareManagement and Prevention of Nausea and Vomiting Supportive Care
Study Suggests Long-acting Patch that Prevents Nausea and Vomiting Can Be Given in Combination with Intravenous Medication (February 9, 2010)
Use of a combination of Sancuso® (granisetron transdermal system; a patch that delivers granisetron through the skin for up to five days) and intravenous granisetron appears to be safe and feasible. This approach may provide immediate and extended... Continue Reading
More Management and Prevention of Nausea and Vomiting Supportive CareManagement and Prevention of Neutropenia Supportive Care
Celebrities Stand Up to Cancer (September 14, 2009)
Celebrities and Amgen are joining forces to Stand Up to Cancer™—in the form of a public service campaign designed to educate cancer patients and caregivers about managing the increased risk of infection during cancer treatment. Chemotherapy is an... Continue Reading
Amgen Helps Reduce Out-of-pocket Costs for Neulasta® (July 2, 2009)Amgen’s Neulasta FIRST STEP™ Program provides assistance to eligible, low-income, commercially-insured chemotherapy patients who need help with their co-insurance or co-payment requirement for Neulasta® (pegfilgrastim). Neulasta is a blood cell growth... Continue Reading
More Management and Prevention of Neutropenia Supportive CareManagement and Prevention of Thrombocytopenia Supportive Care
Nplate Evaluated in Children with Chronic ITP (December 8, 2009)
Among children with chronic immune thrombocytopenic purpura (ITP; an autoimmune disorder characterized by low platelet counts), treatment with Nplate® (romiplostim) stimulates platelet production and appears to be well tolerated. These results were presented... Continue Reading
More Management and Prevention of Thrombocytopenia Supportive CareMantle Cell Non-Hodgkin's Lymphoma
Survivors of Some Childhood Cancers May Face Cognitive Impairment (May 18, 2010)
Survivors of non-central nervous system (CNS) childhood cancers reported a statistically and clinically significantly higher rate of neurocognitive impairment than their cancer-free siblings, according to the results of a study published in the Journal... Continue Reading
Children and Teens Have Better NHL Survival than Young Adults (March 15, 2010)Even after accounting for stage at diagnosis and subtype of non-Hodgkin’s lymphoma (NHL), children and teens with NHL have better survival than young adults with NHL. These results were published in the Archives of Pediatrics and Adolescent Medicine. Non-Hodgkin’s... Continue Reading
Statins May Reduce Effectiveness of Rituxan® in Non-Hodgkin’s Lymphoma (March 8, 2009)Statins May Reduce Effectiveness of Rituxan® in Non-Hodgkin’s Lymphoma Statins may reduce the effectiveness of Rituxan® (rituximab) in treatment of non-Hodgkin’s lymphoma (NHL), according to a recently published article in PLoS Med (the... Continue Reading
Non-Hodgkin’s Lymphoma Survivors May Suffer Symptoms of Post Traumatic Stress (March 8, 2009)Non-Hodgkin’s Lymphoma Survivors May Suffer Symptoms of Post Traumatic Stress Patients who have been diagnosed and treated for non-Hodgkin’s lymphoma may have symptoms of post traumatic stress disorder (PTSD). These finding were recently published... Continue Reading
The American Society of Clinical Oncology 2008: Advances in Treatment of Lymphoma and Chronic Lymphocytic Leukemia (March 8, 2009)The American Society of Clinical Oncology 2008: Advances in Treatment of Lymphoma and Chronic Lymphocytic Leukemia At the 2008 meeting of the American Society of Clinical Oncology (ASCO), there were more than 100 abstracts devoted to the treatment of... Continue Reading
More Mantle Cell Non-Hodgkin's LymphomaMelanoma
Study Evaluates Incidence of Lymphedema Resulting from Cancer Treatment (August 9, 2010)
A systematic review of 47 studies evaluating treatment for melanoma, head and neck cancer, genitourinary cancers, gynecologic cancers, and sarcoma indicates that lymphedema is a common side effect of treatment for these diseases. These findings were recently... Continue Reading
Study Evaluates Melanoma Trends in High-risk Region of United States (July 27, 2010)Melanoma incidence in Hispanic men and African-American women residing in Florida may be higher than in other regions of the United States. These findings were recently published in the journal Archives of Dermatology.[1] Many cases of melanoma are thought... Continue Reading
Ipilimumab Improves Outcomes in Advanced Melanoma (June 7, 2010)Among patients with previously treated, advanced melanoma, treatment with the investigational drug ipilimumab improved overall and progression-free survival. The results of this Phase III clinical trial were presented at the 2010 annual meeting of the... Continue Reading
More Evidence that Indoor Tanning Increases Risk of Melanoma (June 4, 2010)Frequent indoor tanning increases the risk of developing melanoma, according to results recently published in the journal Cancer Epidemiology, Biomarkers & Prevention.[1] Each year in the Unites States, an estimated 28 million people visit an indoor... Continue Reading
How Much Follow-up Is Appropriate for Melanoma Survivors? (June 2, 2010)Once survivors of Stage III melanoma reach a certain time period of recovery, the frequency and intensity of follow-up does not appear to be associated with discovery of resectable first relapses, according to the results of a study published early online... Continue Reading
More MelanomaMesothelioma
MVP Does Not Provide Benefit in Mesothelioma Patients (May 21, 2008)
MVP Does Not Provide Benefit in Mesothelioma Patients The chemotherapy agent Navelbine® (vinorelbine) may improve outcomes for patients with malignant pleural mesothelioma. However, the combination chemotherapy regimen referred to as MVP (mitoxantrone,... Continue Reading
Minimally Invasive Endoscopic Procedure Shows Promise for Detecting Lung Cancer (February 8, 2008)Minimally Invasive Endoscopic Procedure Shows Promise for Detecting Lung Cancer Use of a minimally invasive technique called endoscopy to detect lung cancer may be more effective than more complicated and invasive standard procedures. These findings were... Continue Reading
More MesotheliomaMetastatic Breast Cancer
FDA Advisory Committee Recommends that Avastin No Longer Be Approved for Breast Cancer (July 29, 2010)
CC Archive: Breast Cancer Metastatic, FDA news The Oncology Drugs Advisory Committee (ODAC) of the United States Food and Drug Administration (FDA) has voted 12 to one that Avastin® (bevacizumab) in combination with paclitaxel should no longer be approved... Continue Reading
Olaparib Active Against Advanced Ovarian Cancer and Breast Cancer with BRCA Mutations (July 20, 2010)Previously treated advanced breast and ovarian cancer patients with BRCA1 or BRCA2 gene mutation may benefit from treatment with the oral investigational drug olaparib. These findings were recently published in the journal The Lancet.[1],[2] Although... Continue Reading
Metastases from Breast Cancer May Differ from Primary Tumor (June 9, 2010)It appears that in metastatic breast cancer, the biologic characteristics of liver metastases sometimes differ from those of the primary tumor. This finding may affect treatment choices for metastases. Results of this retrospective study were presented... Continue Reading
Herceptin plus Epirubicin and Cyclophosphamide Tolerable and Effective for HER2-positive Metastatic Breast Cancer (March 31, 2010)For women with metastatic, HER2-positive breast cancer, the combination of Herceptin® (trastuzumab) with epirubicin and cyclophosphamide appears to offer a promising treatment option with a relatively low rate of heart complications. These results... Continue Reading
Neratinib Active in Women with Advanced HER2-positive Breast Cancer (March 16, 2010)Among women with advanced HER2-positive breast cancer, the investigational drug neratinib produced promising response rates and progression-free survival. The results of this Phase II clinical trial were published in the Journal of Clinical Oncology. Twenty... Continue Reading
More Metastatic Breast CancerMetastatic Stage IV (D) Prostate Cancer
Provenge® for Hormone-refractory Prostate Cancer (August 11, 2010)
Among men with metastatic, hormone-refractory prostate cancer, the immunotherapy agent Provenge® (sipuleucel-T) improves survival by roughly four months. The findings from this Phase III study were recently published in The New England Journal of Medicine.[1] The... Continue Reading
Study Explores Prostate Cancer Among Men with Low PSA Levels (July 30, 2010)In a large U.S. cancer database, 14% of prostate cancer diagnoses occurred among men with a prostate-specific antigen (PSA) level of 4.0 ng/mL or lower. More than half of these men had cancer that was considered “low-risk,” but roughly three-quarters... Continue Reading
Prostate Cancer and the Increased Risk of Blood Clots (April 23, 2010)Men with prostate cancer are at a higher risk for several types of thromboembolic diseases (blood clots), with men undergoing endocrine therapy having the highest risk, according to the results of a study published in the Lancet Oncology.[1] In general,... Continue Reading
Targeted Agents plus Chemotherapy Effective for Hormone-refractory Prostate Cancer (April 7, 2010)The combination of Avastin® (bevacizumab), Thalomid® (thalidomide), and Taxotere® (docetaxel) is highly active in hormone-refractory prostate cancer, according to the results of a study published early online in the Journal of Clinical Oncology.[1] The... Continue Reading
Provenge® Prolongs Survival in Hormone Refractory Prostate Cancer (March 22, 2010)The immunotherapy agent Provenge® (sipuleucel-T) significantly prolongs overall survival in men with metastatic, hormone-refractory prostate cancer, according to follow-up data presented at the 2010 Genitourinary Cancers Symposium in San Francisco.... Continue Reading
More Metastatic Stage IV (D) Prostate CancerMetastatic/Stage IVB Cervical Cancer
January Is National Cervical Cancer Awareness Month (March 8, 2009)
January Is National Cervical Cancer Awareness Month As the month of January brings cervical cancer into focus, it’s a great time to increase public understanding of the disease, including its prevalence, approaches to screening and prevention, treatment... Continue Reading
Updates in the Management of Gynecologic Cancers (May 27, 2008)Updates in the Management of Gynecologic Cancers: A Report from the 39th Annual Meeting of the Society of Gynecologic Oncologists The 39th Annual Meeting of the Society of Gynecologic Oncologists (SGO) was held in Tampa, Florida, from March 9 to 12, 2008,... Continue Reading
More Metastatic/Stage IVB Cervical CancerMiscellaneous
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More MiscellaneousMultiple Myeloma
Maintenance Therapy with Revlimid Slows Myeloma Progression (June 3, 2010)
Maintenance therapy with RevlimidÒ (lenalidomide) slowed disease progression by 54% among patients with multiple myeloma who had undergone high-dose chemotherapy and autologous stem cell transplantation. Interim results of this Phase III study will be... Continue Reading
Kepivance Reduces Toxicity of High-dose Therapy for Multiple Myeloma (March 24, 2010)Among patients undergoing high-dose therapy and autologous stem cell transplantation for multiple myeloma, a three-day short course of Kepivance® (palifermin) reduces the toxicity of treatment. These results were published in the Annals of Oncology. Multiple... Continue Reading
Complete Remission Predicts for Long Survival in Multiple Myeloma (March 22, 2010)Achieving a complete remission was the dominant prognostic factor for long survival in patients with multiple myeloma, according to a large retrospective review published in Bone Marrow Transplantation.1 Multiple myeloma is a cancer of the blood that... Continue Reading
Benefit of Velcade on Myeloma Survival Added to Prescribing Information (March 5, 2010)The U.S. Food and Drug Administration (FDA) has approved expanded prescribing information for Velcade® (bortezomib). Velcade’s label now includes results from the VISTA study, which show that Velcade improves long-term overall survival among patients... Continue Reading
Addition of Velcade® and Revlimid® to Autologous Stem Cell Transplantation Produces Promising Results in Older Patients with Multiple Myeloma (January 7, 2010)In a Phase II clinical trial, treatment of older multiple myeloma patients with Velcade® (bortezomib) induction therapy, reduced-intensity tandem autologous stem cell transplantation, and Revlimid® (lenalidomide) consolidation-maintenance therapy produced... Continue Reading
More Multiple MyelomaMyelodysplastic Syndrome
Vidaza® Improves Survival in Higher-risk Myelodysplastic Syndromes (March 6, 2009)
According to the results of a Phase III clinical trial, treatment with Vidaza® (azacitidine) results in better survival than conventional care among patients with higher-risk myelodysplastic syndromes (MDS). These results were published in Lancet Oncology. Myelodysplastic... Continue Reading
The American Society of Clinical Oncology 2008: Highlights of Treatment of Hematological Malignancies (January 30, 2009)The American Society of Clinical Oncology 2008: Highlights of Treatment of Hematological Malignancies The 2008 annual meeting of the American Society of Clinical Oncology (ASCO), held in Chicago, Illinois, again revealed advances in the treatment of... Continue Reading
New Risk Model for MDS Applies to All Stages of Disease (December 31, 2008)New Risk Model for MDS Applies to All Stages of Disease A new risk model for myelodysplastic syndrome (MDS) provides survival projections for all stages of the disease and has proven superior to the International Prognostic Scoring System (IPSS) that... Continue Reading
Older Age Does Not Affect Survival in Patients with AML or MDS Who Undergo Mini-transplants (December 30, 2008)Older Age Does Not Affect Survival in Patients with AML or MDS Who Undergo Mini-transplants Age should not be a barrier for non-myeloablative allogeneic stem cell transplantation in patients with acute myeloid leukemia (AML) or myelodysplastic syndrome... Continue Reading
Vidaza® Approved for High-risk MDS (August 22, 2008)Vidaza® Approved for High-risk MDS The US Food and Drug Administration (FDA) has approved Vidaza® (azacitadine) for the treatment of high-risk myelodysplastic syndromes. Vidaza is already approved for MDS that is categorized into all five French American... Continue Reading
More Myelodysplastic SyndromeN
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More NNeuroblastoma
Neuroblastoma Survival has Improved (May 11, 2010)
Between 1979 and 2005, ten-year overall survival with neuroblastoma improved from 34.9% to 65%. The results of this study, conducted in Italy, were published in the Journal of Clinical Oncology. Neuroblastoma is a disease in which cancerous cells form... Continue Reading
Immunotherapy Improves Outcomes for Patients with High-risk Neuroblastoma (May 21, 2009)According to the results of a Phase III clinical trial that will be presented at the 2009 annual meeting of the American Society of Clinical Oncology (ASCO), use of an investigational immunotherapy treatment reduced the risk of relapse and improved survival... Continue Reading
More NeuroblastomaNews
Experts Agree that Action is Needed to Address Cancer Care in Poorer Countries (September 8, 2010)
The Global Task Force on Expanded Access to Cancer Care and Control in Developing Countries (GTF.CCC), made up of global health and oncology experts, works toward developing and implementing strategies to provide poorer countries with cancer prevention... Continue Reading
Preventive Surgery Reduces Cancer Risk in Women with BRCA1 or BRCA2 Mutations (September 8, 2010)Among women with a BRCA1 or BRCA2 gene mutation, prophylactic mastectomy (preventive removal of the breasts) reduces the risk of getting breast cancer. Prophylactic salpingo-oophorectomy (preventive removal of the fallopian tubes and ovaries) reduces... Continue Reading
Brothers of Prostate Cancer Patients Undergo More Diagnostic Testing (September 7, 2010)Some of the elevated risk of prostate cancer among those with a family history of the disease may be due to increased prostate cancer testing and detection in this population. These findings were recently published in the Journal of the National Cancer... Continue Reading
Addition of Sutent to Tarceva Does Not Improve Overall Survival with Advanced Non-Small Cell Lung Cancer (September 7, 2010)Among patients with previously treated non-small cell lung cancer, the combination of Sutent® (sunitinib) and Tarceva® (erlotinib) delays cancer progression but does not improve overall survival compared with Tarceva alone. The results of this Phase... Continue Reading
Alcohol Linked with Lobular Breast Cancer (September 3, 2010)Although alcohol is a well-established risk factor for breast cancer, it may be more strongly linked with lobular breast cancer than with ductal breast cancer. These results were published in the Journal of the National Cancer Institute. Research suggests... Continue Reading
More NewsNon-Hodgkin's Lymphoma
Istodax Active against Refractory Cutaneous T-cell Lymphoma (August 31, 2010)
Final results from a Phase II clinical trial provide additional evidence that Istodax® (romidepsin) is active against refractory cutaneous T-cell lymphoma. These results were published in the Journal of Clinical Oncology. Cutaneous T-cell lymphoma (CTCL)... Continue Reading
Hepatitis B Virus Linked with Non-Hodgkin’s Lymphoma (August 17, 2010)Individuals with chronic hepatitis B virus (HBV) infection may have an increased risk of developing non-Hodgkin’s lymphoma (NHL), according to findings recently published in The Lancet Oncology. Hepatitis B is a virus that causes inflammation of the... Continue Reading
High Circulating Vitamin D Levels Don’t Reduce Risk of Less Common Cancers (July 13, 2010)High levels of vitamin D in the bloodstream do not appear to reduce the risk of seven less common cancers: endometrial, esophageal, stomach, ovarian, pancreatic, kidney, and non-Hodgkin’s lymphoma. In fact, there was a suggestion that people with the... Continue Reading
Maintenance Therapy with Rituxan Prolongs Lymphoma Remission (May 26, 2010)Among patients with follicular lymphoma who responded to initial treatment with chemotherapy and Rituxan® (rituximab), those who received an additional two years of Rituxan as maintenance therapy remained free of lymphoma progression for longer than... Continue Reading
Survivors of Some Childhood Cancers May Face Cognitive Impairment (May 18, 2010)Survivors of non-central nervous system (CNS) childhood cancers reported a statistically and clinically significantly higher rate of neurocognitive impairment than their cancer-free siblings, according to the results of a study published in the Journal... Continue Reading
More Non-Hodgkin's LymphomaO
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More OOsteosarcoma
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More OsteosarcomaOther News Topics (not Types of Cancer)
Marital Separation Impacts Cancer Survival (September 17, 2009)
Individuals who are separated from their spouse at the time of their cancer diagnosis have a lower survival rate than other unmarried patients (including never married, divorced, widowed), according to the results of a study published in Cancer.[1] Past... Continue Reading
More Other News Topics (not Types of Cancer)Ovarian Cancer
Continued Chemotherapy in Advanced Ovarian Cancer (August 9, 2010)
Continuing chemotherapy following initial treatment of advanced ovarian cancer may improve survival, according to a study published in Cancer. Ovarian cancer has the highest mortality rate of all gynecologic cancers. It is the fifth leading cause of cancer... Continue Reading
Olaparib Active Against Advanced Ovarian Cancer and Breast Cancer with BRCA Mutations (July 20, 2010)Previously treated advanced breast and ovarian cancer patients with BRCA1 or BRCA2 gene mutation may benefit from treatment with the oral investigational drug olaparib. These findings were recently published in the journal The Lancet.[1],[2] Although... Continue Reading
High Circulating Vitamin D Levels Don’t Reduce Risk of Less Common Cancers (July 13, 2010)High levels of vitamin D in the bloodstream do not appear to reduce the risk of seven less common cancers: endometrial, esophageal, stomach, ovarian, pancreatic, kidney, and non-Hodgkin’s lymphoma. In fact, there was a suggestion that people with the... Continue Reading
Combination of Trabectedin and Pegylated Liposomal Doxorubicin Modestly Delays Progression of Recurrent Ovarian Cancer (July 9, 2010)The combination of the investigational agent trabectedin with pegylated liposomal doxorubicin (PLD) resulted in a 1.5-month improvement in progression-free survival in women with recurrent ovarian cancer. Final information about overall survival is not... Continue Reading
Olaparib Shows Promise in High-grade Serous Ovarian Cancer (June 16, 2010)Advanced serous ovarian cancer responds to single-agent treatment with olaparib, according to the results of a Phase II study presented at the 2010 annual meeting of the American Society of Clinical Oncology.[1] Ovarian cancer has the highest mortality... Continue Reading
More Ovarian CancerP
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More PPain Management Supportive Care
Acupuncture Relieves Pain, Improves Functioning After Neck Surgery (April 28, 2010)
Acupuncture may reduce pain and improve functioning among patients with cancer who have undergone surgery to the neck, according to a study published in the Journal of Clinical Oncology.[1] As well, acupuncture may relieve xerostomia (dry mouth) among... Continue Reading
Onsolis Approved for Breakthrough Pain (July 27, 2009)Onsolis (fentanyl buccal soluble film) has been approved by the U.S. Food and Drug Administration for the treatment of breakthrough cancer pain.[1] Pain may be a side effect of cancer treatment or may be caused by the cancer itself. If not adequately... Continue Reading
More Pain Management Supportive CarePancreatic Cancer
Gemzar plus Avastin Does Not Improve Survival in Advanced Pancreatic Cancer (July 14, 2010)
Results from a recent Phase III trial indicate that the addition of the targeted therapy Avastin® (bevacizumab) to the chemotherapy drug Gemzar® (gemcitabine) does not improve survival in advanced pancreatic cancer. These findings were reported in the... Continue Reading
High Circulating Vitamin D Levels Don’t Reduce Risk of Less Common Cancers (July 13, 2010)High levels of vitamin D in the bloodstream do not appear to reduce the risk of seven less common cancers: endometrial, esophageal, stomach, ovarian, pancreatic, kidney, and non-Hodgkin’s lymphoma. In fact, there was a suggestion that people with the... Continue Reading
Afinitor Delays Progression of Advanced Pancreatic Neuroendocrine Tumors (July 8, 2010)In a recent Phase III trial, the targeted therapy Afinitor® (everolimus) more than doubled progression-free survival time among patients with advanced pancreatic neuroendocrine tumors (NET). Results of this study were presented at the 12th World Congress... Continue Reading
Improved Survival in Metastatic Pancreatic Cancer (June 24, 2010)It appears that the chemotherapy combination known as FOLFIRINOX may improve survival in metastatic pancreatic cancer over a current standard-of-care, Gemzar® (gemcitabine). The results of this Phase III study were presented at the 2010 annual meeting... Continue Reading
AMG 479 Produces Promising Results in Metastatic Pancreatic Cancer (June 7, 2010)According to the results of a Phase II clinical trial, treatment of metastatic pancreatic cancer with a combination of AMG 479 and Gemzar® (gemcitabine) resulted in better progression-free and overall survival than treatment with Gemzar alone. These... Continue Reading
More Pancreatic CancerProgressive Relapsed Hodgkin's Lymphoma
Allogeneic Stem Cell Transplantation Viable for Children and Adolescents with Relapsed Hodgkin’s Lymphoma (September 24, 2009)
Children and adolescents with relapsed Hodgkin’s lymphoma respond well to allogeneic stem cell transplantation, according to the results of a study published in Blood.[1] Although children and adolescents with Hodgkin’s lymphoma have an excellent... Continue Reading
Hodgkin’s Survivors at Increased Risk of Stroke (June 24, 2009)Hodgkin’s Survivors at Increased Risk of Stroke Patients who have been treated with radiation therapy for Hodgkin’s lymphoma have an elevated risk of stroke. These results were published in the Journal of the National Cancer Institute. Hodgkin’s... Continue Reading
Autologous Stem Cell Transplantation Effective for Relapsed Hodgkin’s Lymphoma (March 8, 2009)Autologous Stem Cell Transplantation Effective for Relapsed Hodgkin’s Lymphoma Autologous stem cell transplantation is effective for patients with Hodgkin’s lymphoma that has progressed following prior therapies. These results were recently... Continue Reading
More Progressive Relapsed Hodgkin's LymphomaProstate Cancer
Brothers of Prostate Cancer Patients Undergo More Diagnostic Testing (September 7, 2010)
Some of the elevated risk of prostate cancer among those with a family history of the disease may be due to increased prostate cancer testing and detection in this population. These findings were recently published in the Journal of the National Cancer... Continue Reading
Death from Other Causes Among Men with Early-stage Prostate Cancer (August 26, 2010)Among men with early-stage prostate cancer, assessment of other health problems may help guide prostate cancer treatment decisions; men who are likely to die of causes other than prostate cancer may not benefit from aggressive prostate cancer treatment.... Continue Reading
Study Evaluates Physician Use of Finasteride for Prostate Cancer Prevention (August 18, 2010)Recent research indicates that 64% of urologists and 80% of primary care physicians surveyed do not prescribe finasteride for prevention of prostate cancer in high-risk men. These findings were recently published in the journal Cancer Epidemiology, Biomarkers... Continue Reading
Provenge® for Hormone-refractory Prostate Cancer (August 11, 2010)Among men with metastatic, hormone-refractory prostate cancer, the immunotherapy agent Provenge® (sipuleucel-T) improves survival by roughly four months. The findings from this Phase III study were recently published in The New England Journal of Medicine.[1] The... Continue Reading
Study Evaluates Incidence of Lymphedema Resulting from Cancer Treatment (August 9, 2010)A systematic review of 47 studies evaluating treatment for melanoma, head and neck cancer, genitourinary cancers, gynecologic cancers, and sarcoma indicates that lymphedema is a common side effect of treatment for these diseases. These findings were recently... Continue Reading
More Prostate CancerQ
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More RadiopharmaceuticalRectal Cancer
Rectal Cancer Increasing in People Under 40 (September 2, 2010)
Although still relatively uncommon in young people, the incidence of rectal cancer appears to be increasing in this population. These results were published in the journal Cancer. Colorectal cancer is the second leading cause of cancer death in the United... Continue Reading
Pathological Complete Response Predicts Better Outcomes in Locally Advanced Rectal Cancer Patients (August 25, 2010)Among patients with locally advanced rectal cancer, a complete disappearance of detectable cancer (pathological complete response) after preoperative chemoradiation therapy is linked with better long-term outcomes. These findings were recently published... Continue Reading
Antibiotic Sponge Ineffective at Preventing Surgical Infection (August 12, 2010)Patients undergoing colorectal surgery are reported to experience an increased incidence of surgical-site infection with the addition of a gentamicin-collagen sponge enclosed at the surgery site. These findings were recently published in the New England... Continue Reading
Radioembolization plus Fluorouracil Active in Colorectal Cancer Patients with Liver Metastases (July 2, 2010)Radioembolization plus the chemotherapy agent fluorouracil slows cancer progression for colorectal cancer patients whose disease has progressed following prior treatment with chemotherapy and have metastases limited to the liver. These findings were recently... Continue Reading
Depression May Persist With Metastatic Cancer (May 27, 2010)A substantial number of patients with metastatic cancer may suffer from depression which tends to persist and grow more severe toward the end of life, according to the results of a study published early online in the Journal of Clinical Oncology.[1] While... Continue Reading
More Rectal CancerRecurrent Anal Cancer
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More Recurrent Anal CancerRecurrent Bladder Cancer
Cystoscopy Alone Is the Most Cost-effective Way to Monitor for Recurrence of Bladder Cancer (March 9, 2010)
The addition of a urine test to standard cystoscopy screening in order to monitor for bladder cancer recurrence unnecessarily increases the cost of monitoring as well as the risk for a false-positive result and does not improve tumor detection, according... Continue Reading
More Recurrent Bladder CancerRecurrent Breast Cancer
Olaparib Active Against Advanced Ovarian Cancer and Breast Cancer with BRCA Mutations (July 20, 2010)
Previously treated advanced breast and ovarian cancer patients with BRCA1 or BRCA2 gene mutation may benefit from treatment with the oral investigational drug olaparib. These findings were recently published in the journal The Lancet.[1],[2] Although... Continue Reading
Racial Disparity in Breast Cancer Outcomes Among Underinsured (June 30, 2010)Underinsured African-Americans have worse breast cancer survival outcomes than their underinsured White counterparts, according to the results of a study published early online in the Journal of the National Caner Institute.[i] The disparity in breast... Continue Reading
Eribulin Improves Survival with Metastatic Breast Cancer (June 8, 2010)Among women with previously treated, locally recurrent or metastatic breast cancer, treatment with the investigational chemotherapy drug eribulin mesylate improved overall survival by about 2.5 months. The results of this Phase III clinical trial were... Continue Reading
Optimal Outcomes with Vascular Endothelial Growth Factor (VEGF) Inhibitors Require Appropriate Hypertension Assessment, Monitoring, and Management (May 28, 2010)An expert panel provided consensus recommendations for appropriate prevention, surveillance and treatment of hypertension (high blood pressure) in patients treated with vascular endothelial growth factor (VEGF) signaling pathway inhibitors. These recommendations... Continue Reading
Neratinib Active in Women with Advanced HER2-positive Breast Cancer (March 16, 2010)Among women with advanced HER2-positive breast cancer, the investigational drug neratinib produced promising response rates and progression-free survival. The results of this Phase II clinical trial were published in the Journal of Clinical Oncology. Twenty... Continue Reading
More Recurrent Breast CancerRecurrent Cervical Cancer
Avastin® Shows Promise in Treatment of Cervical Cancer (March 8, 2009)
Avastin® Shows Promise in Treatment of Cervical Cancer According to the results of a Phase II clinical trial, the targeted therapy Avastin® (bevacizumab) warrants further investigation in the treatment of persistent or recurrent squamous cell carcinoma... Continue Reading
January Is National Cervical Cancer Awareness Month (March 8, 2009)January Is National Cervical Cancer Awareness Month As the month of January brings cervical cancer into focus, it’s a great time to increase public understanding of the disease, including its prevalence, approaches to screening and prevention, treatment... Continue Reading
Neulasta® on First Day of Chemotherapy May Be More Convenient for Gynecologic Cancers (March 8, 2009)Neulasta® on First Day of Chemotherapy May Be More Convenient for Gynecologic Cancers The administration of the blood cell growth factor Neulasta® (pegfilgrastim) on the first day of chemotherapy among women with gynecologic cancers may be as effective... Continue Reading
More Recurrent Cervical CancerRecurrent Gastric Cancer
Clinical Trial for Advanced Gastric Cancer Now Enrolling Patients (July 16, 2010)
Gastric cancer forms in the tissues and lining of the stomach. Current treatment options include surgery, chemotherapy, and radiation. The current standard of care for metastatic gastric cancer is systemic therapy. Research is ongoing to determine which... Continue Reading
Herceptin® Improves Survival with HER2-positive Gastric Cancer (June 2, 2009)Herceptin® Improves Survival with HER2-positive Gastric Cancer According to the results of a Phase III clinical trial presented at the 2009 annual meeting of the American Society of Clinical Oncology (ASCO), treatment with a combination of chemotherapy... Continue Reading
More Recurrent Gastric CancerRecurrent Liver Cancer
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More Recurrent Liver CancerRecurrent Lung Cancer - Non-Small Cell
Addition of Sutent to Tarceva Does Not Improve Overall Survival with Advanced Non-Small Cell Lung Cancer (September 7, 2010)
Among patients with previously treated non-small cell lung cancer, the combination of Sutent® (sunitinib) and Tarceva® (erlotinib) delays cancer progression but does not improve overall survival compared with Tarceva alone. The results of this Phase... Continue Reading
Study Evaluates Safety of Avastin and Chemotherapy in Non–Squamous Non–Small Cell Lung Cancer (August 3, 2010)A large Phase IV study confirms that the safety and efficacy reported in Phase III trials of Avastin® (bevacizumab) plus standard chemotherapy for patients with advanced non-squamous non-small cell lung cancer translate into the clinical practice setting.... Continue Reading
Large Study Confirms that Vandetanib Is Active in Previously Treated Non–Small Cell Lung Cancer (June 15, 2010)The combination of vandetanib plus Taxotere resulted in longer survival without cancer progression than Taxotere alone among patients with previously-treated non–small cell lung cancer (NSCLC). These findings were recently published in the journal The... Continue Reading
November Is National Lung Cancer Awareness Month (November 6, 2009)As the month of November brings lung cancer into focus, it’s time to increase public understanding of the disease, including its prevalence, approaches to screening and prevention, treatment options, and resources that offer updated lung cancer information... Continue Reading
Addition of Avastin® to Tarceva® Does Not Appear to Improve Survival in Patients with Advanced Non–Small Cell Lung Cancer (March 8, 2009)Addition of Avastin® to Tarceva® Does Not Appear to Improve Survival in Patients with Advanced Non–Small Cell Lung Cancer According to the results of a Phase III clinical trial, treatment with Avastin® (bevacizumab) plus Tarceva® (erlotinib) did... Continue Reading
More Recurrent Lung Cancer - Non-Small CellRecurrent Lung Cancer - Small Cell
November Is National Lung Cancer Awareness Month (November 6, 2009)
As the month of November brings lung cancer into focus, it’s time to increase public understanding of the disease, including its prevalence, approaches to screening and prevention, treatment options, and resources that offer updated lung cancer information... Continue Reading
More Recurrent Lung Cancer - Small CellRecurrent Melanoma
Metastatic Melanoma Patients Undergoing Treatment with Dacarbazine and Interferon May Benefit from the Addition of Thymosin α 1 (April 15, 2010)
The addition of thymosin Metastatic Melanoma Patients Undergoing Treatment with Dacarbazine and Interferon May Benefit from the Addition of Thymosin α 1 (Tα1) to dacarbazine and interferon improved overall survival and progression-free survival compared... Continue Reading
Preventive Dental Care Reduces Osteonecrosis of the Jaw Associated with Bisphosphonates (March 8, 2009)Preventive Dental Care Reduces Osteonecrosis of the Jaw Associated with Bisphosphonates Patients who undergo preventive dental care prior to receiving therapy with bisphosphonates have a significantly reduced risk of developing osteonecrosis of the jaw.... Continue Reading
More Recurrent MelanomaRecurrent Multiple Myeloma
Kepivance Reduces Toxicity of High-dose Therapy for Multiple Myeloma (March 24, 2010)
Among patients undergoing high-dose therapy and autologous stem cell transplantation for multiple myeloma, a three-day short course of Kepivance® (palifermin) reduces the toxicity of treatment. These results were published in the Annals of Oncology. Multiple... Continue Reading
Velcade® plus Perifosine Shows Promise in Relapsed or Refractory Multiple Myeloma (March 8, 2009)Velcade® plus Perifosine Shows Promise in Relapsed or Refractory Multiple Myeloma Among patients with relapsed or refractory multiple myeloma previously treated with Velcade® (bortezomib), 40% responded to treatment with a combination of Velcade and... Continue Reading
Multiple Myeloma Treatment Does Not Affect the Outcome of Stem Cell Transplant (March 8, 2009)Multiple Myeloma Treatment Does Not Affect the Outcome of Stem Cell Transplant A recently published study indicates that the type of initial chemotherapy for multiple myeloma has no impact on the outcome of patients who later undergo autologous stem cell... Continue Reading
Preventive Dental Care Reduces Osteonecrosis of the Jaw Associated with Bisphosphonates (March 8, 2009)Preventive Dental Care Reduces Osteonecrosis of the Jaw Associated with Bisphosphonates Patients who undergo preventive dental care prior to receiving therapy with bisphosphonates have a significantly reduced risk of developing osteonecrosis of the jaw.... Continue Reading
More Recurrent Multiple MyelomaRecurrent Non-Hodgkin's Lymphoma
Survivors of Some Childhood Cancers May Face Cognitive Impairment (May 18, 2010)
Survivors of non-central nervous system (CNS) childhood cancers reported a statistically and clinically significantly higher rate of neurocognitive impairment than their cancer-free siblings, according to the results of a study published in the Journal... Continue Reading
Children and Teens Have Better NHL Survival than Young Adults (March 15, 2010)Even after accounting for stage at diagnosis and subtype of non-Hodgkin’s lymphoma (NHL), children and teens with NHL have better survival than young adults with NHL. These results were published in the Archives of Pediatrics and Adolescent Medicine. Non-Hodgkin’s... Continue Reading
Veltuzumab Effective for Refractory Non-Hodgkin’s Lymphoma (July 28, 2009)Veltuzumab is safe and effective for patients with relapsed/refractory B-cell non-Hodgkin’s lymphoma, according to the results of a study published in the Journal of Clinical Oncology.[1] Non-Hodgkin’s lymphoma (NHL) is a form of cancer that begins... Continue Reading
New and Novel Agents for the Treatment of Non-Hodgkin’s Lymphoma: A Report from the 2008 Meeting of the American Society of Hematology (March 8, 2009)New and Novel Agents for the Treatment of Non-Hodgkin’s Lymphoma: A Report from the 2008 Meeting of the American Society of Hematology The 2008 ASH meeting featured several reports of new agents that are showing promise in the treatment of Non-Hodgkin’s... Continue Reading
Zevalin® Effective for Patients with Follicular Lymphoma Following an Autologous Transplant (March 8, 2009)Zevalin® Effective for Patients with Follicular Lymphoma Following an Autologous Transplant Zevalin® (Yttrium-90 [(90)Y] ibritumomab tiuxetan) appears to provide effective, long-term anticancer responses for patients with follicular lymphoma whose cancer... Continue Reading
More Recurrent Non-Hodgkin's LymphomaRecurrent Ovarian Cancer
Olaparib Active Against Advanced Ovarian Cancer and Breast Cancer with BRCA Mutations (July 20, 2010)
Previously treated advanced breast and ovarian cancer patients with BRCA1 or BRCA2 gene mutation may benefit from treatment with the oral investigational drug olaparib. These findings were recently published in the journal The Lancet.[1],[2] Although... Continue Reading
Combination of Trabectedin and Pegylated Liposomal Doxorubicin Modestly Delays Progression of Recurrent Ovarian Cancer (July 9, 2010)The combination of the investigational agent trabectedin with pegylated liposomal doxorubicin (PLD) resulted in a 1.5-month improvement in progression-free survival in women with recurrent ovarian cancer. Final information about overall survival is not... Continue Reading
Olaparib Active Against Advanced Ovarian Cancer in Women with BRCA Mutations (May 5, 2010)Olaparib, an investigational targeted therapy, resulted in a 61.5% response rate among women with platinum-sensitive, advanced ovarian cancer and a BRCA gene mutation. These results were recently published in the Journal of Clinical Oncology.[1] Although... Continue Reading
Farletuzumab Shows Promise in Relapsed Ovarian Cancer (October 7, 2009)According to the results of a Phase II clinical trial, the investigational drug farletuzumab may have anticancer activity in the treatment of relapsed ovarian cancer when combined with chemotherapy. These results were presented at a European cancer conference. Many... Continue Reading
September Is National Ovarian Cancer Awareness Month (September 1, 2009)As the month of September brings ovarian cancer into focus, it’s time to increase public understanding about the disease, including its prevalence, approaches to screening and prevention, treatment options, and resources that offer updated ovarian cancer... Continue Reading
More Recurrent Ovarian CancerRecurrent Pancreatic Cancer
November Is National Pancreatic Cancer Awareness Month (November 5, 2009)
As the month of November brings pancreatic cancer into focus, it’s time to increase public understanding of the disease, including its prevalence, approaches to screening and prevention, treatment options, and resources that offer updated pancreatic... Continue Reading
More Recurrent Pancreatic CancerRecurrent Testicular Cancer
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More Recurrent Testicular CancerRecurrent Uterine Cancer
Neulasta® on First Day of Chemotherapy May Be More Convenient for Gynecologic Cancers (March 8, 2009)
Neulasta® on First Day of Chemotherapy May Be More Convenient for Gynecologic Cancers The administration of the blood cell growth factor Neulasta® (pegfilgrastim) on the first day of chemotherapy among women with gynecologic cancers may be as effective... Continue Reading
More Recurrent Uterine CancerRecurrent/Relapsed Rectal Cancer
Radioembolization plus Fluorouracil Active in Colorectal Cancer Patients with Liver Metastases (July 2, 2010)
Radioembolization plus the chemotherapy agent fluorouracil slows cancer progression for colorectal cancer patients whose disease has progressed following prior treatment with chemotherapy and have metastases limited to the liver. These findings were recently... Continue Reading
Preventive Treatment Reduces Skin Side Effects of Vectibix (February 16, 2010)Among patients with metastatic colorectal cancer treated with the targeted therapy Vectibix® (panitumumab), preventive skin care reduces the occurrence of skin side effects. These results were published in the Journal of Clinical Oncology. Colorectal... Continue Reading
Vectibix Improves Outcome of Previously Treated Colorectal Cancer (January 27, 2010)Among patients with previously treated, metastatic colorectal cancer, the addition of the targeted therapy Vectibix® (panitumumab) to chemotherapy delayed cancer progression. This benefit was only observed in patients whose tumors did not contain... Continue Reading
Hemoglobin Level Among Factors that May Predict Outcome in Rectal Cancer (March 8, 2009)Hemoglobin Level Among Factors that May Predict Outcome in Rectal Cancer Researchers in the United States have recently published results indicating that certain prognostic factors may predict outcome for patients undergoing radiation for locally recurrent... Continue Reading
Early Skin Treatment Reduces Skin Reactions in Colorectal Cancer Patients Treated with Vectibix® (March 8, 2009)Early Skin Treatment Reduces Skin Reactions in Colorectal Cancer Patients Treated with Vectibix® Among patients with colorectal cancer, skin treatment beginning on the day prior to therapy with Vectibix® (panitumumab) significantly reduces skin side... Continue Reading
More Recurrent/Relapsed Rectal CancerRefactory/Recurrent Prostate Cancer
Jevtana Approved for Hormone-refractory Prostate Cancer (June 21, 2010)
Jevtana® (cabazitaxel), a new chemotherapy drug, was approved for use in combination with prednisone for the treatment of patients with metastatic hormone-refractory prostate cancer previously treated with a Taxotere® (docetaxel)-containing regimen. Prostate... Continue Reading
Provenge Approved for Advanced Prostate Cancer (April 30, 2010)Provenge® (sipuleucel-T), a type of immunotherapy, has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of asymptomatic or minimally symptomatic, metastatic, hormone-refractory prostate cancer.[1] Prostate cancer is... Continue Reading
Investigational Drug Shows Activity in Advanced Prostate Cancer (April 26, 2010)An investigational anti-androgen drug called MDV3100 has shown encouraging anti-tumor activity in patients with progressive, metastatic, hormone-resistant prostate cancer, according to the preliminary results of a study published early online in the... Continue Reading
Prostate Cancer and the Increased Risk of Blood Clots (April 23, 2010)Men with prostate cancer are at a higher risk for several types of thromboembolic diseases (blood clots), with men undergoing endocrine therapy having the highest risk, according to the results of a study published in the Lancet Oncology.[1] In general,... Continue Reading
Targeted Agents plus Chemotherapy Effective for Hormone-refractory Prostate Cancer (April 7, 2010)The combination of Avastin® (bevacizumab), Thalomid® (thalidomide), and Taxotere® (docetaxel) is highly active in hormone-refractory prostate cancer, according to the results of a study published early online in the Journal of Clinical Oncology.[1] The... Continue Reading
More Refactory/Recurrent Prostate CancerRenal Cancer
High Circulating Vitamin D Levels Don’t Reduce Risk of Less Common Cancers (July 13, 2010)
High levels of vitamin D in the bloodstream do not appear to reduce the risk of seven less common cancers: endometrial, esophageal, stomach, ovarian, pancreatic, kidney, and non-Hodgkin’s lymphoma. In fact, there was a suggestion that people with the... Continue Reading
Optimal Outcomes with Vascular Endothelial Growth Factor (VEGF) Inhibitors Require Appropriate Hypertension Assessment, Monitoring, and Management (May 28, 2010)An expert panel provided consensus recommendations for appropriate prevention, surveillance and treatment of hypertension (high blood pressure) in patients treated with vascular endothelial growth factor (VEGF) signaling pathway inhibitors. These recommendations... Continue Reading
Chronic Hepatitis C Infection May Increase Risk for Developing Renal Cell Carcinoma (April 22, 2010)Chronic infection with hepatitis C virus may increase the risk of renal cell cancer (RCC), according to results published in the journal Cancer Epidemiology, Biomarkers and Prevention.[1] The kidneys are filled with tiny tubules that clean and filter... Continue Reading
Cryoablation Effective for Renal Cancer (March 4, 2010)Stereotactic percutaneous cryoablation and laparoscopic renal cryoablation are effective treatments for selected patients with kidney cancer, according to the results of two studies published in the Journal of Urology.1,2 The kidneys are each filled... Continue Reading
Some Chinese Herbs May Increase Risk of Urinary Tract Cancer (February 18, 2010)The use of Chinese herbal products that contain aristolochic acid is associated with an increased risk of urinary tract cancer, according to the results of a study published in the Journal of the National Cancer Institute.[1] Previous research has... Continue Reading
More Renal CancerRetinoblastoma
Long-term Retinoblastoma Survivors at Greater Risk of Dying from Subsequent Cancers (May 11, 2009)
Long-term retinoblastoma survivors are at a greater risk of dying from subsequent cancers and this elevated risk extends beyond 40 years, according to the results of a study published in the Journal of the National Cancer Institute.1 Retinoblastoma... Continue Reading
More RetinoblastomaS
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More SSarcoma
Study Evaluates Incidence of Lymphedema Resulting from Cancer Treatment (August 9, 2010)
A systematic review of 47 studies evaluating treatment for melanoma, head and neck cancer, genitourinary cancers, gynecologic cancers, and sarcoma indicates that lymphedema is a common side effect of treatment for these diseases. These findings were recently... Continue Reading
Study Evaluates Anthracycline-related Heart Problems in Childhood Cancer Survivors (May 28, 2010)Children with particular variants of drug-metabolizing genes may be more likely than other children to develop heart problems after low doses of anthracycline chemotherapy. The results of this study will be presented at the 2010 annual meeting of the... Continue Reading
Study Evaluates Anthracycline-related Heart Problems in Childhood Cancer Survivors (May 28, 2010)Children with particular variants of drug-metabolizing genes may be more likely than other children to develop heart problems after low doses of anthracycline chemotherapy. The results of this study will be presented at the 2010 annual meeting of the... Continue Reading
High-risk Soft Tissue Sarcoma Patients Benefit from Targeted Heat Therapy Combined with Chemotherapy (May 7, 2010)A technique called regional hyperthermia (RHT) makes chemotherapy more effective and improves outcomes in patients with localized, high-risk soft tissue sarcoma, according to the results of a study recently published in the journal The Lancet.[1] These... Continue Reading
Children with Ewing’s Sarcoma or Astrocytoma Most Likely to Experience Late Recurrence (February 19, 2010)Late recurrence of childhood cancers appears to occur most often in Ewing’s sarcoma and astrocytoma, according to the results of a study published in the Journal of the National Cancer Institute. As cancer treatment has improved and evolved, the number... Continue Reading
More SarcomaScreening/Prevention Anal Cancer
Immunosuppression Increases Risk of HPV-related Cancers in AIDS Patients (August 20, 2009)
The risk of HPV-related cancers is elevated among AIDS patients. This risk continues to increase as patients’ immune systems become more compromised, according to the results of a study published in the Journal of the National Cancer Institute.[1] Human... Continue Reading
More Screening/Prevention Anal CancerScreening/Prevention Bladder Cancer
Components of Processed Meat May Increase Risk of Bladder Cancer (August 10, 2010)
People who consume a large amount of nitrite and nitrate from processed meat may be at an increased risk for developing bladder cancer, according to a study published in Cancer. Bladder cancer is diagnosed in as many as 60,000 individuals annually in... Continue Reading
Painters May Have Higher Risk of Bladder Cancer (July 29, 2010)Occupational exposures appear to increase bladder cancer risk in painters, according to a study published in Occupational and Environmental Medicine. Workers in certain occupations may face an increased risk of cancer due to exposures that they encounter... Continue Reading
Exposure to Aromatic Amines Poses Long-term Risk of Bladder Cancer (June 25, 2010)Workers exposed to aromatic amines continued to experience an increased risk of bladder cancer even 30 years after exposure, according to the results of a follow-up study published in the Journal of the National Cancer Institute.[1] Aromatic amines are... Continue Reading
Vitamins C, D, and E Don’t Reduce Risk of Bladder Cancer (June 7, 2010)Long-term use of vitamin C, vitamin D, or vitamin E does not appear to reduce the risk of bladder cancer. These results were presented at the 2010 annual meeting of the American Urological Association. Each year in the United States, close to 53,000 men... Continue Reading
Study Evaluates Long-term Effects of Arsenic in Drinking Water on Bladder Cancer (June 4, 2010)Death rate from bladder cancer continues to rise 20 years after exposure to high levels of arsenic in drinking water. These findings were recently presented at the 105th Annual Scientific Meeting of the American Urological Association (AUA).[1] Drinking... Continue Reading
More Screening/Prevention Bladder CancerScreening/Prevention Breast Cancer
Preventive Surgery Reduces Cancer Risk in Women with BRCA1 or BRCA2 Mutations (September 8, 2010)
Among women with a BRCA1 or BRCA2 gene mutation, prophylactic mastectomy (preventive removal of the breasts) reduces the risk of getting breast cancer. Prophylactic salpingo-oophorectomy (preventive removal of the fallopian tubes and ovaries) reduces... Continue Reading
Alcohol Linked with Lobular Breast Cancer (September 3, 2010)Although alcohol is a well-established risk factor for breast cancer, it may be more strongly linked with lobular breast cancer than with ductal breast cancer. These results were published in the Journal of the National Cancer Institute. Research suggests... Continue Reading
Additional Research on Menopausal Hormone Therapy and Breast Cancer (August 24, 2010)A recent study of menopausal hormone therapy and risk of breast cancer reported that risk may vary by body weight and the type of hormone therapy. These results were published in Cancer Epidemiology, Biomarkers, & Prevention. As women reach menopause... Continue Reading
Breast Density and Hormone Therapy Add to Breast Cancer Risk (August 4, 2010)Postmenopausal women with high breast density are at an increased risk of developing breast cancer, according to the results of a study published in the Journal of Clinical Oncology.[1] This risk increases with the use of hormone therapy. Breast density... Continue Reading
Screening Rates Among Older Americans (July 15, 2010)More older Americans are undergoing screening for colon cancer, but the rates for breast cancer screening remain the same, according to a government report released on July 6, 2010.[1] The best “treatment” of cancer is preventing its occurrence in... Continue Reading
More Screening/Prevention Breast CancerScreening/Prevention Cervical Cancer
HPV Vaccine Protects Against Genital Warts and Precancerous Growths (July 30, 2010)
Results from a recent international study indicate that the vaccine Gardasil® (quadrivalent human papillomavirus [types 6, 11, 16, 18] recombinant vaccine) protects against genital warts and low-grade precancerous changes to the cervix, vulva, and vagina.... Continue Reading
Many Physicians Fail to Adhere to New Cervical Cancer Screening Guidelines (July 12, 2010)Apparently, old habits die hard: less than one-third of physicians report compliance with the updated guidelines for cervical cancer screening that suggest longer intervals between screening for women with normal test results. The results of this survey... Continue Reading
More Than Half of Young Adults in New Relationships Infected with HPV (April 26, 2010)More than half of young adults in a new sexual relationship are infected with human papillomavirus (HPV), and of those 44% were infected with an HPV type that causes cancer, according to the results of a groundbreaking study called the HITCH Cohort... Continue Reading
Cervical Vaccine Provides Little Benefit for Older Women (March 4, 2010)Women over the age of 40 are not likely to benefit from a vaccine designed to prevent human papillomavirus (HPV), according to the results of a study published in the Journal of the National Cancer Institute.1 HPV has been shown to cause cervical cancer. Human... Continue Reading
Cervarix® Protection Extends Beyond Six Years (February 12, 2010)Cervarix®—a vaccine that reduces the risk of cervical cancer by protecting against two high-risk types of human papillomavirus (HPV)—remains effective for more than six years. These results were published in the Lancet. Human papillomaviruses... Continue Reading
More Screening/Prevention Cervical CancerScreening/Prevention Colon Cancer
Screening Rates Among Older Americans (July 15, 2010)
More older Americans are undergoing screening for colon cancer, but the rates for breast cancer screening remain the same, according to a government report released on July 6, 2010.[1] The best “treatment” of cancer is preventing its occurrence in... Continue Reading
Rates of Adenoma Detection Linked to Risk of Interval Colorectal Cancer (May 18, 2010)Endoscopists who detect tumors or polyps (adenomas) at a higher rate during colonoscopy screening for colorectal cancer tend to produce a lower risk for interval cancer among their patients, according to a study published in the New England Journal of... Continue Reading
Coffee and Soft Drinks Not Associated with Increased Risk of Colon Cancer (May 12, 2010)Consumption of coffee and sugary soft drinks does not increase the risk of colon cancer, according to the results of a study published early online in the Journal of the National Cancer Institute.[1] High tea consumption, on the other hand, might be... Continue Reading
Colorectal Cancer Screening with Flexible Sigmoidoscopy Reduces Incidence and Death (May 6, 2010)Among individuals between 55 and 64 years of age, one screening using flexible sigmoidoscopy can reduce risk of developing colorectal cancer and dying from the disease, according to a study published in The Lancet. Colon cancer is the second leading... Continue Reading
Lower Use of Diagnostic Testing May Explain Higher Colorectal Cancer Mortality in African Americans (April 6, 2010)The higher incidence and mortality from colorectal cancer among African Americans compared with Whites may be due to differences in health care utilization rather than differences in susceptibility to cancer, according to a study published in the... Continue Reading
More Screening/Prevention Colon CancerScreening/Prevention Esophageal Cancer
Reassuring Findings Regarding Oral Bisphosphonates and Esophageal Cancer (August 23, 2010)
Oral bisphosphonates—drugs commonly used to prevent or treat osteoporosis—do not appear to increase the risk of esophageal cancer. These results were published in the Journal of the American Medical Association. Osteoporosis—a condition characterized... Continue Reading
High Circulating Vitamin D Levels Don’t Reduce Risk of Less Common Cancers (July 13, 2010)High levels of vitamin D in the bloodstream do not appear to reduce the risk of seven less common cancers: endometrial, esophageal, stomach, ovarian, pancreatic, kidney, and non-Hodgkin’s lymphoma. In fact, there was a suggestion that people with the... Continue Reading
Excess Body Weight Linked with More Than 100,000 New Cancer Diagnoses Each Year in U.S. (November 9, 2009)According to estimates from the American Institute for Cancer Research (AICR), excess body weight may be responsible for more than 100,000 new cancer diagnoses each year in the United States. Excess body weight is increasingly recognized as a risk factor... Continue Reading
New Study Confirms Increased Incidence of Adenocarcinoma of the Esophagus in White Americans (March 8, 2009)New Study Confirms Increased Incidence of Adenocarcinoma of the Esophagus in White Americans Researchers from the National Institutes of Health have reported that between 1975 and 2004, the incidence of adenocarcinoma of the esophagus increased by 463%... Continue Reading
Obesity and Acid Reflux Significantly Increase Risk of Developing Esophageal Cancer (March 8, 2009)Obesity and Acid Reflux Significantly Increase Risk of Developing Esophageal Cancer According to an article recently published in the journal Gut, individuals who are obese and have frequent symptoms of acid reflux have a significantly increased risk... Continue Reading
More Screening/Prevention Esophageal CancerScreening/Prevention Gastric Cancer
High Circulating Vitamin D Levels Don’t Reduce Risk of Less Common Cancers (July 13, 2010)
High levels of vitamin D in the bloodstream do not appear to reduce the risk of seven less common cancers: endometrial, esophageal, stomach, ovarian, pancreatic, kidney, and non-Hodgkin’s lymphoma. In fact, there was a suggestion that people with the... Continue Reading
Cancers of the Lower Stomach have Increased in Young Whites (May 7, 2010)Although overall rates of noncardia gastric cancer (cancer of the lower stomach) have decreased in the United States, rates have increased in whites between the ages of 25 and 39 years. These findings were recently published in the Journal of the American... Continue Reading
Aspirin May Reduce Risk of Stomach Cancer (August 28, 2009)Regular aspirin use may reduce the risk of distal stomach cancer (cancer in the lower part of the stomach). These results were published in the American Journal of Epidemiology. Cancer of the stomach is called gastric cancer. Gastric adenocarcinoma is... Continue Reading
Fruits and Vegetables Reduce Risk of Stomach Cancer (March 8, 2009)Fruits and Vegetables Reduce Risk of Stomach Cancer According to an article recently published in the American Journal of Epidemiology, diets higher in vegetables and fruits and lower in foods common in Western diets (such as processed meats, soft drinks,... Continue Reading
More Screening/Prevention Gastric CancerScreening/Prevention Leukemia
Cell Phone Towers and Childhood Cancer Risk (July 1, 2010)
Recent findings indicate that children who are exposed to radiofrequency fields from cell phone towers before birth do not have an increased risk of early childhood cancer. This study was published in the British Medical Journal. The health effects—notably,... Continue Reading
Formaldehyde Exposure May Increase Risk of Blood and Lymphatic Cancers (June 23, 2009)Formaldehyde Exposure May Increase Risk of Blood and Lymphatic Cancers Industrial workers who are exposed to formaldehyde may be at an increased risk of dying from blood and lymphatic cancers, particularly myeloid leukemia but also Hodgkin’s lymphoma... Continue Reading
Cyclophosphamide May Increase Cancer Risk Among Patients with Rheumatoid Arthritis (March 8, 2009)Cyclophosphamide May Increase Cancer Risk Among Patients with Rheumatoid Arthritis A large study conducted in Canada reveals that patients who are treated for rheumatoid arthritis (RA) with the drug cyclophosphamide may have an increased risk for developing... Continue Reading
Being Overweight Associated with Increased Risk of Several Cancers (March 8, 2009)Being Overweight Associated with Increased Risk of Several Cancers Excess bodyweight increases the risk of developing several types of cancer, according to results recently published in The Lancet. It is estimated that in the United States, one out of... Continue Reading
More Screening/Prevention LeukemiaScreening/Prevention Liver Cancer
Liver Cancer Incidence is on the Rise in the United States (May 25, 2010)
From 2001 to 2006, the incidence of hepatocellular carcinoma (HCC) increased significantly with an average increase of 3.5% annually. This analysis was recently reported in the Centers for Disease Control and Prevention’s (CDC) Morbidity and Mortality... Continue Reading
Liver Cancer Often Linked to Diabetes (May 4, 2010)Diabetes increases the risk of hepatocellular carcinoma (HCC) and may account for a greater number of HCC cases in the United States than any other single HCC risk factor. These results were presented at the 101st annual meeting of the American Association... Continue Reading
Women with Hypothyroidism at Increased Risk of Liver Cancer (June 22, 2009)Women with Hypothyroidism at Increased Risk of Liver Cancer Long-term hypothyroidism in women significantly increases the risk of developing hepatocellular carcinoma (liver cancer), according to the results of a study published in Hepatology.[1] The liver... Continue Reading
Genetic Characteristics of Hepatitis B Associated with Risk of Liver Cancer (March 8, 2009)Genetic Characteristics of Hepatitis B Associated with Risk of Liver Cancer Different genetic characteristics of the hepatitis B virus (HBV) are associated with varying risks of developing hepatocellular carcinoma (HCC), the most common form of liver... Continue Reading
Liver Cancer Screening in Patients with Chronic Hepatitis B and C Improves Survival (March 8, 2009)Liver Cancer Screening in Patients with Chronic Hepatitis B and C Improves Survival Researchers in Hong Kong have reported that screening patients with chronic hepatitis for liver cancer improves liver cancer survival rates and may improve chances for... Continue Reading
More Screening/Prevention Liver CancerScreening/Prevention Lung Cancer - Non-Small Cell
Estrogen Alone Does Not Increase Lung Cancer Incidence or Mortality in Postmenopausal Women (August 30, 2010)
Among postmenopausal women, hormone therapy with estrogen alone does not appear to increase the risk of getting or dying from lung cancer. These results were published in the Journal of the National Cancer Institute. As women reach menopause and beyond,... Continue Reading
Vitamin B6 Associated with Lower Risk of Lung Cancer (June 28, 2010)Individuals with high blood levels of vitamin B6 may be less likely to develop lung cancer compared with their counterparts with lower vitamin B6 levels, according to the results of a study published in the Journal of the American Medical Association.[1] Lung... Continue Reading
Some Blood Pressure Drugs May Raise Cancer Risk (June 23, 2010)It appears that angiotensin-receptor blockers (ARBs), a widely used class of blood pressure drugs, may slightly increase the risk of cancer. These findings were published in the Lancet Oncology. Angiotensin-receptor blockers work by blocking angiotensin... Continue Reading
Lung Cancer Risk and Traffic-related Air Pollution (May 20, 2010)Researchers report a modest association between air pollution resulting from traffic and risk of lung cancer. These findings were recently published in the journal Cancer Epidemiology, Biomarkers & Prevention.[1] Although the relationship between... Continue Reading
High Rate of False-positive Results in Lung Cancer Screening with CT Scan (April 28, 2010)Screening for lung cancer using computed tomography (CT) scans can yield a high rate of false-positive results, according to a study published in the Annals of Internal Medicine. False-positive results are risky because they may lead to invasive follow-up... Continue Reading
More Screening/Prevention Lung Cancer - Non-Small CellScreening/Prevention Lung Cancer - Small Cell
Estrogen Alone Does Not Increase Lung Cancer Incidence or Mortality in Postmenopausal Women (August 30, 2010)
Among postmenopausal women, hormone therapy with estrogen alone does not appear to increase the risk of getting or dying from lung cancer. These results were published in the Journal of the National Cancer Institute. As women reach menopause and beyond,... Continue Reading
Vitamin B6 Associated with Lower Risk of Lung Cancer (June 28, 2010)Individuals with high blood levels of vitamin B6 may be less likely to develop lung cancer compared with their counterparts with lower vitamin B6 levels, according to the results of a study published in the Journal of the American Medical Association.[1] Lung... Continue Reading
Some Blood Pressure Drugs May Raise Cancer Risk (June 23, 2010)It appears that angiotensin-receptor blockers (ARBs), a widely used class of blood pressure drugs, may slightly increase the risk of cancer. These findings were published in the Lancet Oncology. Angiotensin-receptor blockers work by blocking angiotensin... Continue Reading
High Rate of False-positive Results in Lung Cancer Screening with CT Scan (April 28, 2010)Screening for lung cancer using computed tomography (CT) scans can yield a high rate of false-positive results, according to a study published in the Annals of Internal Medicine. False-positive results are risky because they may lead to invasive follow-up... Continue Reading
Combined Hormone Replacement Therapy May Increase Women’s Risk of Lung Cancer (April 2, 2010)Women who receive hormone replacement therapy with estrogen plus progestin may have an increased risk of developing lung cancer, according to a study published in the Journal of Clinical Oncology.[1] Hormone replacement therapy (HRT) is often prescribed... Continue Reading
More Screening/Prevention Lung Cancer - Small CellScreening/Prevention Melanoma
Study Evaluates Melanoma Trends in High-risk Region of United States (July 27, 2010)
Melanoma incidence in Hispanic men and African-American women residing in Florida may be higher than in other regions of the United States. These findings were recently published in the journal Archives of Dermatology.[1] Many cases of melanoma are thought... Continue Reading
More Evidence that Indoor Tanning Increases Risk of Melanoma (June 4, 2010)Frequent indoor tanning increases the risk of developing melanoma, according to results recently published in the journal Cancer Epidemiology, Biomarkers & Prevention.[1] Each year in the Unites States, an estimated 28 million people visit an indoor... Continue Reading
Indoor Tanning May Be Addictive in Some Individuals (April 29, 2010)Researchers report that some individuals may meet criteria for addiction to indoor tanning and are more likely to exhibit other addictive behaviors and affective disturbance. These results were recently published in the journal Archives of Dermatology.[1] Each... Continue Reading
More Evidence of Prevalence of Youth Tanning Bed Use (April 15, 2010)Use of tanning beds by youths age 11-17 in the UK is widespread according to results recently published in the British Medical Journal.[1] Use of tanning beds has been linked with an increased risk of melanoma, the most deadly type of skin cancer. Each... Continue Reading
Hispanics and African Americans Present with More Advanced Melanoma than Whites (December 30, 2009)Researchers from Florida have reported that Hispanics and African Americans present with more advanced melanomas than their White counterparts. These results were published in the Archives of Dermatology. The three most common types of skin cancer are... Continue Reading
More Screening/Prevention MelanomaScreening/Prevention Non-Hodgkin's Lymphoma
Hepatitis B Virus Linked with Non-Hodgkin’s Lymphoma (August 17, 2010)
Individuals with chronic hepatitis B virus (HBV) infection may have an increased risk of developing non-Hodgkin’s lymphoma (NHL), according to findings recently published in The Lancet Oncology. Hepatitis B is a virus that causes inflammation of the... Continue Reading
High Circulating Vitamin D Levels Don’t Reduce Risk of Less Common Cancers (July 13, 2010)High levels of vitamin D in the bloodstream do not appear to reduce the risk of seven less common cancers: endometrial, esophageal, stomach, ovarian, pancreatic, kidney, and non-Hodgkin’s lymphoma. In fact, there was a suggestion that people with the... Continue Reading
Number of Obesity-related Cancers Is Growing (October 3, 2009)In 2008, excess body weight was responsible for over 124,000 new cancer diagnoses in Europe. These results were presented at a major European cancer conference. Obesity is increasingly being recognized as a risk factor not only for cancer development,... Continue Reading
Cyclophosphamide May Increase Cancer Risk Among Patients with Rheumatoid Arthritis (March 8, 2009)Cyclophosphamide May Increase Cancer Risk Among Patients with Rheumatoid Arthritis A large study conducted in Canada reveals that patients who are treated for rheumatoid arthritis (RA) with the drug cyclophosphamide may have an increased risk for developing... Continue Reading
Being Overweight Associated with Increased Risk of Several Cancers (March 8, 2009)Being Overweight Associated with Increased Risk of Several Cancers Excess bodyweight increases the risk of developing several types of cancer, according to results recently published in The Lancet. It is estimated that in the United States, one out of... Continue Reading
More Screening/Prevention Non-Hodgkin's LymphomaScreening/Prevention Ovarian Cancer
High Circulating Vitamin D Levels Don’t Reduce Risk of Less Common Cancers (July 13, 2010)
High levels of vitamin D in the bloodstream do not appear to reduce the risk of seven less common cancers: endometrial, esophageal, stomach, ovarian, pancreatic, kidney, and non-Hodgkin’s lymphoma. In fact, there was a suggestion that people with the... Continue Reading
Promising Results for Ovarian Cancer Screening Strategy (June 3, 2010)In a study of postmenopausal women at average-risk of ovarian cancer, promising results were obtained with an ovarian cancer screening strategy that combined information about trends in CA-125 blood test results and age, followed as needed by transvaginal... Continue Reading
One Step Closer to Early Detection of Ovarian Cancer (April 13, 2010)A four-biomarker screening assay detected 86% of early-stage ovarian cancers with a 98% specificity level; this leads researchers to conclude that the assay could eventually become the first-line test in a two-step strategy for early detection of the... Continue Reading
Test Available for Pre-surgical Evaluation of Ovarian Mass (March 11, 2010)For women who require surgery for an ovarian mass, the OVA1™ test may help identify the most appropriate type of surgeon. The test assesses the likelihood that cancer is present; when cancer is likely, surgery may best be performed by a gynecologic... Continue Reading
Regular Aspirin Use May Reduce Risk of Ovarian Cancer (February 17, 2010)According to results from the Iowa Women’s Health Study, regular aspirin use may reduce the risk of developing ovarian cancer but does not appear to affect the risk of endometrial cancer. These results were published in Cancer Epidemiology, Biomarkers,... Continue Reading
More Screening/Prevention Ovarian CancerScreening/Prevention Pancreatic Cancer
High Circulating Vitamin D Levels Don’t Reduce Risk of Less Common Cancers (July 13, 2010)
High levels of vitamin D in the bloodstream do not appear to reduce the risk of seven less common cancers: endometrial, esophageal, stomach, ovarian, pancreatic, kidney, and non-Hodgkin’s lymphoma. In fact, there was a suggestion that people with the... Continue Reading
Soda Consumption May Be Linked to Pancreatic Cancer (February 9, 2010)Individuals who consumed two or more sugary soft drinks per week experienced a statistically significant increased risk of pancreatic cancer when compared with individuals who did not consume soft drinks, according to the results of a study conducted... Continue Reading
Excess Body Weight Linked with More Than 100,000 New Cancer Diagnoses Each Year in U.S. (November 9, 2009)According to estimates from the American Institute for Cancer Research (AICR), excess body weight may be responsible for more than 100,000 new cancer diagnoses each year in the United States. Excess body weight is increasingly recognized as a risk factor... Continue Reading
November Is National Pancreatic Cancer Awareness Month (November 5, 2009)As the month of November brings pancreatic cancer into focus, it’s time to increase public understanding of the disease, including its prevalence, approaches to screening and prevention, treatment options, and resources that offer updated pancreatic... Continue Reading
Lynch Syndrome Increases Risk of Pancreatic Cancer (November 2, 2009)Lynch Syndrome, an inherited cause of colorectal cancer that also increases the risk of several other types of cancer, results in a risk of pancreatic cancer that is several times higher than the risk in the general population. These results were published... Continue Reading
More Screening/Prevention Pancreatic CancerScreening/Prevention Prostate Cancer
Brothers of Prostate Cancer Patients Undergo More Diagnostic Testing (September 7, 2010)
Some of the elevated risk of prostate cancer among those with a family history of the disease may be due to increased prostate cancer testing and detection in this population. These findings were recently published in the Journal of the National Cancer... Continue Reading
Study Evaluates Physician Use of Finasteride for Prostate Cancer Prevention (August 18, 2010)Recent research indicates that 64% of urologists and 80% of primary care physicians surveyed do not prescribe finasteride for prevention of prostate cancer in high-risk men. These findings were recently published in the journal Cancer Epidemiology, Biomarkers... Continue Reading
Dogs May Be Able to Smell Prostate Cancer (June 8, 2010)Dogs may be able to smell the presence of prostate cancer in patient urine samples, according to data presented at the 2010 Annual Scientific Meeting of the American Urological Association (AUA). Volatile organic compounds (VOCs) are organic chemical... Continue Reading
PCA3 a More Specific Test for Prostate Cancer (June 4, 2010)For the detection of prostate cancer, a new urine test known as PCA3 produces fewer false-positive test results than the commonly used prostate-specific antigen (PSA) blood test. These results were presented at the 2010 annual meeting of the American... Continue Reading
Prostate Cancer and the Increased Risk of Blood Clots (April 23, 2010)Men with prostate cancer are at a higher risk for several types of thromboembolic diseases (blood clots), with men undergoing endocrine therapy having the highest risk, according to the results of a study published in the Lancet Oncology.[1] In general,... Continue Reading
More Screening/Prevention Prostate CancerScreening/Prevention Rectal Cancer
Rectal Cancer Increasing in People Under 40 (September 2, 2010)
Although still relatively uncommon in young people, the incidence of rectal cancer appears to be increasing in this population. These results were published in the journal Cancer. Colorectal cancer is the second leading cause of cancer death in the United... Continue Reading
Rates of Adenoma Detection Linked to Risk of Interval Colorectal Cancer (May 18, 2010)Endoscopists who detect tumors or polyps (adenomas) at a higher rate during colonoscopy screening for colorectal cancer tend to produce a lower risk for interval cancer among their patients, according to a study published in the New England Journal of... Continue Reading
Colorectal Cancer Screening with Flexible Sigmoidoscopy Reduces Incidence and Death (May 6, 2010)Among individuals between 55 and 64 years of age, one screening using flexible sigmoidoscopy can reduce risk of developing colorectal cancer and dying from the disease, according to a study published in The Lancet. Colon cancer is the second leading... Continue Reading
Lower Use of Diagnostic Testing May Explain Higher Colorectal Cancer Mortality in African Americans (April 6, 2010)The higher incidence and mortality from colorectal cancer among African Americans compared with Whites may be due to differences in health care utilization rather than differences in susceptibility to cancer, according to a study published in the... Continue Reading
Low Levels of Vitamin B6 May Increase Risk of Colorectal Cancer (March 23, 2010)Individuals with low blood levels of an active form of vitamin B6 or low dietary intake of vitamin B6 may have an increased risk of developing colorectal cancer. These results, based on an analysis of several previously published studies, were published... Continue Reading
More Screening/Prevention Rectal CancerScreening/Prevention Uterine Cancer
High Circulating Vitamin D Levels Don’t Reduce Risk of Less Common Cancers (July 13, 2010)
High levels of vitamin D in the bloodstream do not appear to reduce the risk of seven less common cancers: endometrial, esophageal, stomach, ovarian, pancreatic, kidney, and non-Hodgkin’s lymphoma. In fact, there was a suggestion that people with the... Continue Reading
Two Behaviors May Affect Risk of Endometrial Cancer (May 21, 2010)Two recent studies have identified behaviors that may affect risk of endometrial cancer: physical activity, which may reduce risk, and perineal use of talcum powder, which may increase risk. Results from both of these studies were published in Cancer... Continue Reading
Two Behaviors May Affect Risk of Endometrial Cancer (May 21, 2010)Two recent studies have identified behaviors that may affect risk of endometrial cancer: physical activity, which may reduce risk, and perineal use of talcum powder, which may increase risk. Results from both of these studies were published in Cancer... Continue Reading
Regular Aspirin Use May Reduce Risk of Ovarian Cancer (February 17, 2010)According to results from the Iowa Women’s Health Study, regular aspirin use may reduce the risk of developing ovarian cancer but does not appear to affect the risk of endometrial cancer. These results were published in Cancer Epidemiology, Biomarkers,... Continue Reading
Excess Body Weight Linked with More Than 100,000 New Cancer Diagnoses Each Year in U.S. (November 9, 2009)According to estimates from the American Institute for Cancer Research (AICR), excess body weight may be responsible for more than 100,000 new cancer diagnoses each year in the United States. Excess body weight is increasingly recognized as a risk factor... Continue Reading
More Screening/Prevention Uterine CancerSkin Cancer
HPV Infection May Raise Skin Cancer Risk (July 13, 2010)
It appears that infection with certain types of human papillomavirus (HPV) may be linked with the incidence of squamous cell carcinoma, a form of skin cancer. These findings were recently published in the journal BMJ. There are three main types of cancers... Continue Reading
Indoor Tanning May Be Addictive in Some Individuals (April 29, 2010)Researchers report that some individuals may meet criteria for addiction to indoor tanning and are more likely to exhibit other addictive behaviors and affective disturbance. These results were recently published in the journal Archives of Dermatology.[1] Each... Continue Reading
More Evidence of Prevalence of Youth Tanning Bed Use (April 15, 2010)Use of tanning beds by youths age 11-17 in the UK is widespread according to results recently published in the British Medical Journal.[1] Use of tanning beds has been linked with an increased risk of melanoma, the most deadly type of skin cancer. Each... Continue Reading
High Incidence of Non-melanoma Skin Cancer in the U.S. (March 24, 2010)A significant increase in the incidence of non-melanoma skin cancers in the United States since the 1990s has been reported in two studies recently published in the Archives of Dermatology.[1],[2] Non-melanoma skin cancers include basal cell carcinoma... Continue Reading
May Is National Skin Cancer Awareness Month (March 8, 2009)May Is National Skin Cancer Awareness Month As the month of May brings skin cancer into focus, it’s a great time to increase public understanding of the disease, including its prevalence, approaches to screening and prevention, treatment options,... Continue Reading
More Skin CancerSkin Cancer Overview
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More Skin Cancer OverviewSoft Tissue Sarcomas
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More Soft Tissue SarcomasStage I Cervical Cancer
Sentinel Node Biopsy Is a Minimally-invasive, Effective Method for Determining Spread of Cervical Cancer (June 9, 2009)
Sentinel Node Biopsy Is a Minimally-invasive, Effective Method for Determining Spread of Cervical Cancer The majority of women with cervical cancer can safely undergo sentinel node biopsy instead of full pelvic lymph node dissection to determine the spread... Continue Reading
January Is National Cervical Cancer Awareness Month (March 8, 2009)January Is National Cervical Cancer Awareness Month As the month of January brings cervical cancer into focus, it’s a great time to increase public understanding of the disease, including its prevalence, approaches to screening and prevention, treatment... Continue Reading
Robotically-assisted Hysterectomy Appears Effective for Cervical Cancer (March 8, 2009)Robotically-assisted Hysterectomy Appears Effective for Cervical Cancer Robotically-assisted hysterectomy (RAH) in patients with early-stage cervical cancer is at least as effective as traditional open radical hysterectomy (ORH) and produces fewer complications,... Continue Reading
Differences in IMRT Radiation Doses May Complicate Study Results in Gynecological Cancers (March 8, 2009)Differences in IMRT Radiation Doses May Complicate Study Results in Gynecological Cancers Differences between the prescribed dose of radiation in intensity modulated radiation therapy (IMRT) and the dose that’s actually delivered may make comparison... Continue Reading
Updates in the Management of Gynecologic Cancers (May 27, 2008)Updates in the Management of Gynecologic Cancers: A Report from the 39th Annual Meeting of the Society of Gynecologic Oncologists The 39th Annual Meeting of the Society of Gynecologic Oncologists (SGO) was held in Tampa, Florida, from March 9 to 12, 2008,... Continue Reading
More Stage I Cervical CancerStage I Node Negative Breast Cancer
Study Evaluates Impact of Lymph Node Removal in Early-stage Breast Cancer (August 13, 2010)
Early-stage breast cancer patients without evidence of cancer in their sentinel lymph node who did not have additional lymph nodes removed report fewer side effects to the arm and breast than patients who undergo additional lymph node removal. These findings... Continue Reading
Updated Guidelines Address Hormonal Therapy for Breast Cancer (July 21, 2010)Among postmenopausal women with hormone receptor-positive breast cancer, use of an aromatase inhibitor at some point in the course of adjuvant (post-surgery) treatment results in a lower risk of cancer recurrence than use of tamoxifen only. Based on these... Continue Reading
Many Breast Cancer Patients Taking Adjuvant Hormonal Therapy Stop Treatment Early (July 1, 2010)Less than half of early-stage breast cancer patients with hormone-sensitive disease completed the full dose and schedule of their hormonal therapy treatment. These findings were recently published in the Journal of Clinical Oncology.[1] The majority of... Continue Reading
Racial Disparity in Breast Cancer Outcomes Among Underinsured (June 30, 2010)Underinsured African-Americans have worse breast cancer survival outcomes than their underinsured White counterparts, according to the results of a study published early online in the Journal of the National Caner Institute.[i] The disparity in breast... Continue Reading
Gene Mutation Increases Risk of Blood Clots in Breast Cancer Patients Taking Tamoxifen (June 29, 2010)Among women taking tamoxifen for early-stage breast cancer, an inherited gene mutation (Factor V Leiden) may increase the risk of blood clots. These results, which differ from a previous study that evaluated women taking tamoxifen for breast cancer prevention,... Continue Reading
More Stage I Node Negative Breast CancerStage I Ovarian Cancer
September Is National Ovarian Cancer Awareness Month (September 1, 2009)
As the month of September brings ovarian cancer into focus, it’s time to increase public understanding about the disease, including its prevalence, approaches to screening and prevention, treatment options, and resources that offer updated ovarian cancer... Continue Reading
Fertility Preservation Appears to Be Safe for Young Women with Early-stage Ovarian Cancer (August 11, 2009)Preservation of the non-cancerous ovary and the uterus appears to be safe for young women with Stage IA or IC ovarian cancer and allows women to preserve their fertility. These results were published in Cancer. Women who confront a cancer diagnosis at... Continue Reading
Ovarian Cancer National Alliance Announces Eleventh Annual Conference (March 8, 2009)Ovarian Cancer National Alliance Announces Eleventh Annual Conference This year the Ovarian Cancer National Alliance will hold their eleventh annual conference, titled “Creating Currents of Change,” on Tuesday, July 8 through Thursday, July... Continue Reading
Specialty Hospitals Associated with Improved Survival in Early Ovarian Cancer (March 8, 2009)Specialty Hospitals Associated with Improved Survival in Early Ovarian Cancer Hospitals that specialize in care for ovarian cancer are associated with significantly improved survival for women with early ovarian cancer. These results were recently reported... Continue Reading
Further Evidence in Favor of Care for Ovarian Cancer Patients by Gynecologic Oncologists (March 8, 2009)Further Evidence in Favor of Care for Ovarian Cancer Patients by Gynecologic Oncologists According to an article recently published in Gynecologic Oncology, patients under 55 years of age with Stages IC–II ovarian cancer were more likely to receive... Continue Reading
More Stage I Ovarian CancerStage I-II Testicular Cancer
New Genes Linked to Testicular Cancer (June 28, 2010)
Scientists have discovered three new genes associated with testicular cancer, according to the results of a study published in Nature Genetics.[1] Testicular cancer is the most common type of cancer in men ages 15 to 45. The incidence of testicular cancer... Continue Reading
Men with Infertility May Have Increased Risk of Testicular Cancer (March 8, 2009)Men with Infertility May Have Increased Risk of Testicular Cancer Men with infertility are three times more likely to develop testicular cancer compared with fertile men, according to the results of a study published in the Archives of Internal Medicine.[1] The... Continue Reading
Single Dose of Carboplatin as Effective as Radiation Therapy for Testicular Cancer (March 8, 2009)Single Dose of Carboplatin as Effective as Radiation Therapy for Testicular Cancer Among men with Stage I seminoma (a type of testicular cancer), post-surgery treatment with a single dose of the chemotherapy drug carboplatin is as effective as two to... Continue Reading
More Stage I-II Testicular CancerStage I/Smoldering Myeloma Multiple Myeloma
Benefit of Velcade on Myeloma Survival Added to Prescribing Information (March 5, 2010)
The U.S. Food and Drug Administration (FDA) has approved expanded prescribing information for Velcade® (bortezomib). Velcade’s label now includes results from the VISTA study, which show that Velcade improves long-term overall survival among patients... Continue Reading
Velcade® Improves Response Rate After High-dose Melphalan for Myeloma (December 21, 2009)Among patients who have received high-dose melphalan and an autologous stem cell transplant for initial treatment of multiple myeloma, Velcade® (bortezomib) appears to improve treatment response rates. These results were presented at the 2009 meeting... Continue Reading
Revlimid® Delays Progression of Multiple Myeloma (December 18, 2009)Among multiple myeloma patients who have had an autologous stem cell transplant, additional treatment with Revlimid® (lenalidomide) delays cancer progression. These results were released by the National Cancer Institute. Multiple myeloma is a cancer... Continue Reading
Pesticides Linked to Precancerous Blood Disorder (June 24, 2009)Pesticides Linked to Precancerous Blood Disorder Individuals who apply pesticides to crops are twice as likely as the general population to develop a precancerous blood disorder called MGUS (monoclonal gammopathy of undetermined significance), which can... Continue Reading
Formaldehyde Exposure May Increase Risk of Blood and Lymphatic Cancers (June 23, 2009)Formaldehyde Exposure May Increase Risk of Blood and Lymphatic Cancers Industrial workers who are exposed to formaldehyde may be at an increased risk of dying from blood and lymphatic cancers, particularly myeloid leukemia but also Hodgkin’s lymphoma... Continue Reading
More Stage I/Smoldering Myeloma Multiple MyelomaStage II-IV Ovarian Cancer
Continued Chemotherapy in Advanced Ovarian Cancer (August 9, 2010)
Continuing chemotherapy following initial treatment of advanced ovarian cancer may improve survival, according to a study published in Cancer. Ovarian cancer has the highest mortality rate of all gynecologic cancers. It is the fifth leading cause of cancer... Continue Reading
Olaparib Shows Promise in High-grade Serous Ovarian Cancer (June 16, 2010)Advanced serous ovarian cancer responds to single-agent treatment with olaparib, according to the results of a Phase II study presented at the 2010 annual meeting of the American Society of Clinical Oncology.[1] Ovarian cancer has the highest mortality... Continue Reading
Avastin Delays Progression of Advanced Ovarian Cancer (June 8, 2010)In a Phase III clinical trial, the addition of the targeted therapy Avastin® (bevacizumab) to chemotherapy, followed by maintenance therapy with Avastin, slowed cancer progression among women with advanced ovarian, primary peritoneal, or Fallopian tube... Continue Reading
Chemotherapy Drug Patupilone Fails in Advanced Ovarian Cancer (June 2, 2010)The chemotherapy drug patupilone (EPO906) has failed to show a survival advantage over Doxil®/Caelyx® (pegylated liposomal doxorubicin) in patients with advanced ovarian cancer that is resistant to platinum-based therapy. Novartis reported the results... Continue Reading
Olaparib Active Against Advanced Ovarian Cancer in Women with BRCA Mutations (May 5, 2010)Olaparib, an investigational targeted therapy, resulted in a 61.5% response rate among women with platinum-sensitive, advanced ovarian cancer and a BRCA gene mutation. These results were recently published in the Journal of Clinical Oncology.[1] Although... Continue Reading
More Stage II-IV Ovarian CancerStage III Bladder Cancer
Sorry, there are no articles available for this cancer stage.
More Stage III Bladder CancerStage III Melanoma
Study Evaluates Incidence of Lymphedema Resulting from Cancer Treatment (August 9, 2010)
A systematic review of 47 studies evaluating treatment for melanoma, head and neck cancer, genitourinary cancers, gynecologic cancers, and sarcoma indicates that lymphedema is a common side effect of treatment for these diseases. These findings were recently... Continue Reading
Ipilimumab Improves Outcomes in Advanced Melanoma (June 7, 2010)Among patients with previously treated, advanced melanoma, treatment with the investigational drug ipilimumab improved overall and progression-free survival. The results of this Phase III clinical trial were presented at the 2010 annual meeting of the... Continue Reading
How Much Follow-up Is Appropriate for Melanoma Survivors? (June 2, 2010)Once survivors of Stage III melanoma reach a certain time period of recovery, the frequency and intensity of follow-up does not appear to be associated with discovery of resectable first relapses, according to the results of a study published early online... Continue Reading
Adjuvant Radiation Therapy May Improve Melanoma Outcomes (October 5, 2009)Adjuvant radiation therapy improves local control of melanoma following therapeutic lymph node dissection for lymph node-metastatic disease and may improve disease-specific survival, according to the results of a study published in Cancer.[1] Skin cancer... Continue Reading
Pegylated Interferon Alfa-2b Reduces Quality of Life in Stage III Melanoma (July 29, 2009)Although it improves recurrence-free survival, adjuvant (post-surgery) treatment with pegylated interferon alfa-2b adversely affects quality of life among patients with Stage III melanoma. These results were published in the Journal of Clinical Oncology. Skin... Continue Reading
More Stage III MelanomaStage III Testicular Cancer
New Genes Linked to Testicular Cancer (June 28, 2010)
Scientists have discovered three new genes associated with testicular cancer, according to the results of a study published in Nature Genetics.[1] Testicular cancer is the most common type of cancer in men ages 15 to 45. The incidence of testicular cancer... Continue Reading
More Stage III Testicular CancerStage IV (D)/Relapsed Colon Cancer
Radioembolization plus Fluorouracil Active in Colorectal Cancer Patients with Liver Metastases (July 2, 2010)
Radioembolization plus the chemotherapy agent fluorouracil slows cancer progression for colorectal cancer patients whose disease has progressed following prior treatment with chemotherapy and have metastases limited to the liver. These findings were recently... Continue Reading
Optimal Outcomes with Vascular Endothelial Growth Factor (VEGF) Inhibitors Require Appropriate Hypertension Assessment, Monitoring, and Management (May 28, 2010)An expert panel provided consensus recommendations for appropriate prevention, surveillance and treatment of hypertension (high blood pressure) in patients treated with vascular endothelial growth factor (VEGF) signaling pathway inhibitors. These recommendations... Continue Reading
Depression May Persist With Metastatic Cancer (May 27, 2010)A substantial number of patients with metastatic cancer may suffer from depression which tends to persist and grow more severe toward the end of life, according to the results of a study published early online in the Journal of Clinical Oncology.[1] While... Continue Reading
Study Explores Which Patients Respond Best to Vectibix (April 19, 2010)Previous studies have reported that colorectal cancers with mutations in a gene known as KRAS do not respond well to drugs such as Vectibix® (panitumumab). In an effort to expand these findings and further individualize colorectal cancer treatment,... Continue Reading
Cost Versus Benefit Among Chemotherapy Drugs for Metastatic Colorectal Cancer (March 26, 2010)New chemotherapy agents for metastatic colorectal cancer modestly improve survival time but come with substantial costs, according to the results of a study published in the Archives of Internal Medicine.[1] Metastatic colorectal cancer refers to cancer... Continue Reading
More Stage IV (D)/Relapsed Colon CancerStage IV Anal Cancer
No Benefit with Addition of Platinol® to Treatment for Anal Cancer (May 1, 2008)
No Benefit with Addition of Platinol® to Treatment for Anal Cancer Addition of the drug Platinol® (cisplatin) to 5-FU (5-flourouracil), mitomycin, and radiation may not improve outcomes for patients with anal cancer. These findings were recently published... Continue Reading
More Stage IV Anal CancerStage IV Liver Cancer
Combination Chemotherapy Improves Survival with Biliary Tract Cancer (May 17, 2010)
According to the results of a Phase III clinical trial, treatment of locally advanced or metastatic biliary tract cancer with a combination of Gemzar® (gemcitabine) and cisplatin results in better survival and a lower risk of cancer progression than... Continue Reading
Sutent® Not Effective for Advanced Liver Cancer (July 10, 2009)In a Phase II clinical trial, patients with inoperable, advanced hepatocellular (liver) cancer did not benefit from treatment with the targeted therapy Sutent® (sunitinib). The results of this study were published in Lancet Oncology. Hepatocellular carcinoma... Continue Reading
Avastin® plus Tarceva® Shows Promise in Advanced Hepatocellular Carcinoma (March 8, 2009)Avastin® plus Tarceva® Shows Promise in Advanced Hepatocellular Carcinoma According to the results of a Phase II clinical trial, the combination of two targeted therapies-Avastin® (bevacizumab) and Tarceva® (erlotinib)-has anticancer activity in patients... Continue Reading
Nexavar® Effective for Hepatocellular Carcinoma in Asians (March 8, 2009)Nexavar® Effective for Hepatocellular Carcinoma in Asians Researchers from 23 medical centers in Asia have reported that Nexavar® (sorafenib) is effective in patients with advanced hepatocellular carcinoma (liver cancer). The results of this study were... Continue Reading
More Stage IV Liver CancerStage IV Melanoma
Ipilimumab Improves Outcomes in Advanced Melanoma (June 7, 2010)
Among patients with previously treated, advanced melanoma, treatment with the investigational drug ipilimumab improved overall and progression-free survival. The results of this Phase III clinical trial were presented at the 2010 annual meeting of the... Continue Reading
Delcath PHP System Effective Against Liver Metastases (April 22, 2010)Among patients with melanoma that has metastasized (spread) to the liver, the Delcath PHP System™ appears to provide effective treatment to the liver. Full results from a Phase III clinical trial will be presented at the 2010 annual meeting of the... Continue Reading
Metastatic Melanoma Patients Undergoing Treatment with Dacarbazine and Interferon May Benefit from the Addition of Thymosin α 1 (April 15, 2010)The addition of thymosin Metastatic Melanoma Patients Undergoing Treatment with Dacarbazine and Interferon May Benefit from the Addition of Thymosin α 1 (Tα1) to dacarbazine and interferon improved overall survival and progression-free survival compared... Continue Reading
Some Patients with Previously Treated Melanoma Respond to Ipilimumab (December 22, 2009)In a Phase II clinical trial, 11% of patients with previously treated, advanced melanoma experienced a complete or partial disappearance of detectable cancer following treatment with ipilimumab at a dose of 10 mg/kg. These results were published in Lancet... Continue Reading
Sterotactic Radiosurgery Alone Is Preferred Treatment for Newly Diagnosed Brain Metastases (December 9, 2009)Patients with newly diagnosed brain metastases who undergo sterotactic radiosurgery plus whole-brain radiation therapy experience significant memory loss; therefore, stereotactic radiosurgery alone is the preferred method of treatment for these patients,... Continue Reading
More Stage IV MelanomaStage IV Pancreatic Cancer
Gemzar plus Avastin Does Not Improve Survival in Advanced Pancreatic Cancer (July 14, 2010)
Results from a recent Phase III trial indicate that the addition of the targeted therapy Avastin® (bevacizumab) to the chemotherapy drug Gemzar® (gemcitabine) does not improve survival in advanced pancreatic cancer. These findings were reported in the... Continue Reading
Afinitor Delays Progression of Advanced Pancreatic Neuroendocrine Tumors (July 8, 2010)In a recent Phase III trial, the targeted therapy Afinitor® (everolimus) more than doubled progression-free survival time among patients with advanced pancreatic neuroendocrine tumors (NET). Results of this study were presented at the 12th World Congress... Continue Reading
Improved Survival in Metastatic Pancreatic Cancer (June 24, 2010)It appears that the chemotherapy combination known as FOLFIRINOX may improve survival in metastatic pancreatic cancer over a current standard-of-care, Gemzar® (gemcitabine). The results of this Phase III study were presented at the 2010 annual meeting... Continue Reading
AMG 479 Produces Promising Results in Metastatic Pancreatic Cancer (June 7, 2010)According to the results of a Phase II clinical trial, treatment of metastatic pancreatic cancer with a combination of AMG 479 and Gemzar® (gemcitabine) resulted in better progression-free and overall survival than treatment with Gemzar alone. These... Continue Reading
Depression May Persist With Metastatic Cancer (May 27, 2010)A substantial number of patients with metastatic cancer may suffer from depression which tends to persist and grow more severe toward the end of life, according to the results of a study published early online in the Journal of Clinical Oncology.[1] While... Continue Reading
More Stage IV Pancreatic CancerStage IV Rectal Cancer
Radioembolization plus Fluorouracil Active in Colorectal Cancer Patients with Liver Metastases (July 2, 2010)
Radioembolization plus the chemotherapy agent fluorouracil slows cancer progression for colorectal cancer patients whose disease has progressed following prior treatment with chemotherapy and have metastases limited to the liver. These findings were recently... Continue Reading
Depression May Persist With Metastatic Cancer (May 27, 2010)A substantial number of patients with metastatic cancer may suffer from depression which tends to persist and grow more severe toward the end of life, according to the results of a study published early online in the Journal of Clinical Oncology.[1] While... Continue Reading
Study Explores Which Patients Respond Best to Vectibix (April 19, 2010)Previous studies have reported that colorectal cancers with mutations in a gene known as KRAS do not respond well to drugs such as Vectibix® (panitumumab). In an effort to expand these findings and further individualize colorectal cancer treatment,... Continue Reading
Cost Versus Benefit Among Chemotherapy Drugs for Metastatic Colorectal Cancer (March 26, 2010)New chemotherapy agents for metastatic colorectal cancer modestly improve survival time but come with substantial costs, according to the results of a study published in the Archives of Internal Medicine.[1] Metastatic colorectal cancer refers to cancer... Continue Reading
Preventive Treatment Reduces Skin Side Effects of Vectibix (February 16, 2010)Among patients with metastatic colorectal cancer treated with the targeted therapy Vectibix® (panitumumab), preventive skin care reduces the occurrence of skin side effects. These results were published in the Journal of Clinical Oncology. Colorectal... Continue Reading
More Stage IV Rectal CancerStage IV Uterine Cancer
Risk Factors Identified for Uterine Sarcoma Survival (March 8, 2009)
Risk Factors Identified for Uterine Sarcoma Survival Survival for patients diagnosed with uterine leiomyosarcomas may be influenced by several factors. These findings were recently published in the journal Cancer. The uterus is located in the abdomen... Continue Reading
Updates in the Management of Gynecologic Cancers (May 27, 2008)Updates in the Management of Gynecologic Cancers: A Report from the 39th Annual Meeting of the Society of Gynecologic Oncologists The 39th Annual Meeting of the Society of Gynecologic Oncologists (SGO) was held in Tampa, Florida, from March 9 to 12, 2008,... Continue Reading
More Stage IV Uterine CancerStage IV/Metastatic Bladder Cancer
Sorry, there are no articles available for this cancer stage.
More Stage IV/Metastatic Bladder CancerStage IV/Recurrent Esophageal Cancer
Depression May Persist With Metastatic Cancer (May 27, 2010)
A substantial number of patients with metastatic cancer may suffer from depression which tends to persist and grow more severe toward the end of life, according to the results of a study published early online in the Journal of Clinical Oncology.[1] While... Continue Reading
Xeloda® and Eloxatin® Evaluated in Esophageal and Gastric Cancers (March 8, 2009)Xeloda® and Eloxatin® Evaluated in Esophageal and Gastric Cancers According to the results of a Phase III clinical trial published in the New England Journal of Medicine, it may be possible to replace 5-FU (5-fluorouracil) with Xeloda® (capecitabine)... Continue Reading
More Stage IV/Recurrent Esophageal CancerStages 0-I Bladder Cancer
Sorry, there are no articles available for this cancer stage.
More Stages 0-I Bladder CancerStages I-II Anal Cancer
No Benefit with Addition of Platinol® to Treatment for Anal Cancer (May 1, 2008)
No Benefit with Addition of Platinol® to Treatment for Anal Cancer Addition of the drug Platinol® (cisplatin) to 5-FU (5-flourouracil), mitomycin, and radiation may not improve outcomes for patients with anal cancer. These findings were recently published... Continue Reading
More Stages I-II Anal CancerStages I-II Gastric Cancer
Genetic Variant Associated with Poor Outcome for Gastric Cancer (May 24, 2010)
Patients with gastric cancer who have a certain type of inherited variation in the CD44 gene experience a significantly shorter time to disease recurrence (2.1 years) compared with patients without the genetic variation (seven years), according to the... Continue Reading
Adjuvant Chemotherapy Clinical Trial Data from Last 30 Years Evaluated to Determine Benefit in Gastric Cancer (May 14, 2010)A moderate but statistically significant survival benefit was reported with the addition of chemotherapy to surgery in patients with resectable gastric cancer (gastric cancer that can be surgically removed). These findings were recently published in... Continue Reading
In Gastric Cancer Antibiotics Following Surgery Reduce Risk of Second Gastric Cancer (March 8, 2009)In Gastric Cancer Antibiotics Following Surgery Reduce Risk of Second Gastric Cancer Among patients diagnosed with gastric (stomach) cancer, a combination of antibiotics against the bacterium Helicobacter pylori (H. pylori) significantly reduces the risk... Continue Reading
Removal of More Lymph Nodes May Improve Survival in Gastric and Pancreatic Cancers (March 8, 2009)Removal of More Lymph Nodes May Improve Survival in Gastric and Pancreatic Cancers Researchers recommend that at least 15 lymph nodes be removed and examined in patients with early gastric or pancreatic cancers. These results were recently published in... Continue Reading
Combination of Chemotherapy and Immunotherapy Shows Promise for Gastric Cancer (March 8, 2009)Combination of Chemotherapy and Immunotherapy Shows Promise for Gastric Cancer A combination of chemotherapy and immunotherapy (chemoimmunotherapy) may improve overall survival among gastric cancer patients. These findings were recently published in the... Continue Reading
More Stages I-II Gastric CancerStages I-II Melanoma
Study Evaluates Incidence of Lymphedema Resulting from Cancer Treatment (August 9, 2010)
A systematic review of 47 studies evaluating treatment for melanoma, head and neck cancer, genitourinary cancers, gynecologic cancers, and sarcoma indicates that lymphedema is a common side effect of treatment for these diseases. These findings were recently... Continue Reading
May Is National Skin Cancer Awareness Month (March 8, 2009)May Is National Skin Cancer Awareness Month As the month of May brings skin cancer into focus, it’s a great time to increase public understanding of the disease, including its prevalence, approaches to screening and prevention, treatment options,... Continue Reading
More Stages I-II MelanomaStages I-III Esophageal Cancer
Chemoradiotherapy plus Surgery Improves Esophageal Cancer Survival (July 19, 2010)
Among patients with cancer of the esophagus or esophagogastric junction, treatment with chemotherapy and radiation therapy prior to surgery resulted in better overall survival than surgery alone. The results of this Phase III clinical trial were presented... Continue Reading
Less Extensive Treatment Doesn’t Worsen Survival with Early Esophageal Cancer (September 4, 2009)Among patients with esophageal adenocarcinoma that involves only the innermost lining (mucosa) of the esophagus, treatment to remove just the cancer appears to result in similar overall survival as treatment that removes the entire esophagus. These results... Continue Reading
Elderly Patients with Esophageal Cancer Can Tolerate Chemoradiotherapy (March 8, 2009)Elderly Patients with Esophageal Cancer Can Tolerate Chemoradiotherapy Chemoradiotherapy (CRT) is an effective treatment and does not present major toxicity for elderly patients with esophageal cancer, according to the results of a study released in an... Continue Reading
More Stages I-III Esophageal CancerStages I-III Liver Cancer
Combination Chemotherapy Improves Survival with Biliary Tract Cancer (May 17, 2010)
According to the results of a Phase III clinical trial, treatment of locally advanced or metastatic biliary tract cancer with a combination of Gemzar® (gemcitabine) and cisplatin results in better survival and a lower risk of cancer progression than... Continue Reading
Sutent® Not Effective for Advanced Liver Cancer (July 10, 2009)In a Phase II clinical trial, patients with inoperable, advanced hepatocellular (liver) cancer did not benefit from treatment with the targeted therapy Sutent® (sunitinib). The results of this study were published in Lancet Oncology. Hepatocellular carcinoma... Continue Reading
Differences in IMRT Radiation Doses May Complicate Study Results in Liver Cancer (March 8, 2009)Differences in IMRT Radiation Doses May Complicate Study Results in Liver Cancer Differences between the prescribed dose of radiation in intensity modulated radiation therapy (IMRT) and the dose that’s actually delivered may make comparison studies... Continue Reading
Avastin® plus Tarceva® Shows Promise in Advanced Hepatocellular Carcinoma (March 8, 2009)Avastin® plus Tarceva® Shows Promise in Advanced Hepatocellular Carcinoma According to the results of a Phase II clinical trial, the combination of two targeted therapies-Avastin® (bevacizumab) and Tarceva® (erlotinib)-has anticancer activity in patients... Continue Reading
Nexavar® Effective for Hepatocellular Carcinoma in Asians (March 8, 2009)Nexavar® Effective for Hepatocellular Carcinoma in Asians Researchers from 23 medical centers in Asia have reported that Nexavar® (sorafenib) is effective in patients with advanced hepatocellular carcinoma (liver cancer). The results of this study were... Continue Reading
More Stages I-III Liver CancerStages I-III Pancreatic Cancer
November Is National Pancreatic Cancer Awareness Month (November 5, 2009)
As the month of November brings pancreatic cancer into focus, it’s time to increase public understanding of the disease, including its prevalence, approaches to screening and prevention, treatment options, and resources that offer updated pancreatic... Continue Reading
Chemotherapy Improves Pancreatic Cancer Survival (September 9, 2009)Among patients with inoperable pancreatic cancer, Gemzar® (gemcitabine)-based chemotherapy results in longer survival and better quality of life than an alternative treatment regimen consisting of enzyme therapy, nutritional supplements, detoxification,... Continue Reading
Pancreatic Cancer Care Is Inconsistent (July 21, 2009)The quality of care for pancreatic cancer varies considerably among hospitals in the United States, according to the results of a study published in the Journal of the National Cancer Institute.[1] Pancreatic cancer has one of the highest mortality rates... Continue Reading
Neoadjuvant Radiation Improves Survival in Pancreatic Cancer (March 8, 2009)Neoadjuvant Radiation Improves Survival in Pancreatic Cancer Preoperative radiation nearly doubles the survival rate for patients with operable pancreatic cancer, according to the results of a study published in the November 15, 2008 issue of the International... Continue Reading
EndoTAG™-1 Shows Promise in Treatment of Pancreatic Cancer (March 8, 2009)EndoTAG™-1 Shows Promise in Treatment of Pancreatic Cancer According to the results of a Phase II clinical trial, the addition of the investigational drug EndoTAG™-1 to chemotherapy with Gemzar® (gemcitabine) may improve survival among patients with... Continue Reading
More Stages I-III Pancreatic CancerStages I-III Rectal Cancer
Pathological Complete Response Predicts Better Outcomes in Locally Advanced Rectal Cancer Patients (August 25, 2010)
Among patients with locally advanced rectal cancer, a complete disappearance of detectable cancer (pathological complete response) after preoperative chemoradiation therapy is linked with better long-term outcomes. These findings were recently published... Continue Reading
Antibiotic Sponge Ineffective at Preventing Surgical Infection (August 12, 2010)Patients undergoing colorectal surgery are reported to experience an increased incidence of surgical-site infection with the addition of a gentamicin-collagen sponge enclosed at the surgery site. These findings were recently published in the New England... Continue Reading
Most Survivors of Lung and Colorectal Cancer Keep Their Jobs (April 14, 2010)Among people diagnosed with nonmetastatic lung or colorectal cancer, the majority return to work, according to a study recently published in Journal of Clinical Oncology. Those who do leave the workforce tend to have worse prognoses and lower socioeconomic... Continue Reading
Physical Activity Improves Survival of Men with Localized Colorectal Cancer (December 23, 2009)Men who report the most physical activity after a diagnosis of non-metastatic colorectal cancer have a lower risk of death than men who report the least activity. These results were published in the Archives of Internal Medicine. There are over 10 million... Continue Reading
Home Care Nursing Improves Symptom Management (December 4, 2009)Among breast and colorectal cancer patients treated with the oral chemotherapy drug Xeloda® (capecitabine), symptom management was better among patients who received home care nursing than among patients who received standard care. These results were... Continue Reading
More Stages I-III Rectal CancerStages I-III Uterine Cancer
Study Evaluates Incidence of Lymphedema Resulting from Cancer Treatment (August 9, 2010)
A systematic review of 47 studies evaluating treatment for melanoma, head and neck cancer, genitourinary cancers, gynecologic cancers, and sarcoma indicates that lymphedema is a common side effect of treatment for these diseases. These findings were recently... Continue Reading
Laparoscopic Hysterectomy for Endometrial Cancer Associated with Better Quality of Life (August 3, 2010)Laparoscopic hysterectomy for endometrial cancer that is confined to the uterus is associated with less pain, shorter hospital stays, faster recovery, and better quality of life when compared with total abdominal hysterectomy, according to the results... Continue Reading
Vaginal Brachytherapy Effective for Endometrial Cancer (March 17, 2010)Among women who have undergone surgery for high-intermediate risk endometrial cancer, vaginal brachytherapy is as effective as pelvic external beam radiotherapy in the prevention of vaginal recurrence and produces fewer side effects. These results... Continue Reading
Adjuvant Radiation Therapy May Improve Survival in Stage III Uterine Cancer (October 22, 2009)Among women with node-positive Stage III uterine cancer, use of adjuvant (post-surgery) radiation therapy appears to improve survival. These results were published in Gynecologic Oncology. Stage III uterine cancer extends outside the uterus but remains... Continue Reading
Removal of Ovaries May Not Be Necessary in Young Women with Endometrial Cancer (March 8, 2009)Removal of Ovaries May Not Be Necessary in Young Women with Endometrial Cancer According to the results of a study published in the Journal of Clinical Oncology, removal of the ovaries may not be necessary in young women treated with hysterectomy for... Continue Reading
More Stages I-III Uterine CancerStages I-IIIA Lung Cancer - Non-Small Cell
Selenium Does Not Prevent Second Lung Cancers in Patients with Early Non-small Cell Lung Cancer (June 8, 2010)
Supplementation with selenium in patients with Stage IA and IB non-small cell lung cancer does not appear to prevent a second primary lung cancer from developing, according to the results of a Phase III study presented at the 2010 annual meeting of the... Continue Reading
Stereotactic Radiation May Benefit Early Non–Small Cell Lung Cancer Patients Ineligible for Surgery (May 25, 2010)Patients with early-stage non–small cell lung cancer (NSCLC) who were medically unable to undergo surgery to remove their cancer had a 55.8% overall survival at three years following stereotactic body radiation therapy. These findings were recently... Continue Reading
Phase III Trial Evaluates Preoperative Chemotherapy for Non–Small Cell Lung Cancer (May 21, 2010)A Phase III clinical trial of preoperative chemotherapy for non–small cell lung cancer did not provide definitive evidence of a benefit. The results of this prematurely closed study were recently published in the Journal of Clinical Oncology.[1] Lung... Continue Reading
Most Survivors of Lung and Colorectal Cancer Keep Their Jobs (April 14, 2010)Among people diagnosed with nonmetastatic lung or colorectal cancer, the majority return to work, according to a study recently published in Journal of Clinical Oncology. Those who do leave the workforce tend to have worse prognoses and lower socioeconomic... Continue Reading
Concurrent Radiochemotherapy Improves Survival in NSCLC (April 12, 2010)Concurrent chemotherapy delivered with radiation decreased locoregional progression and improved survival in locally advanced non–small cell lung cancer compared with sequential chemotherapy delivered before and/or after radiation. The results of... Continue Reading
More Stages I-IIIA Lung Cancer - Non-Small CellStages II-III Bladder Cancer
Study Evaluates Incidence of Lymphedema Resulting from Cancer Treatment (August 9, 2010)
A systematic review of 47 studies evaluating treatment for melanoma, head and neck cancer, genitourinary cancers, gynecologic cancers, and sarcoma indicates that lymphedema is a common side effect of treatment for these diseases. These findings were recently... Continue Reading
Radical Cystectomy Improves Survival in Stage II Bladder Cancer (May 4, 2010)Radical cystectomy can improve outcomes among patients with muscle-invasive bladder cancer but appears to be underused in this patient population. These results were published in the Journal of the National Cancer Insitute. The bladder is a hollow... Continue Reading
Combined Modality Therapy Preserves Bladder and Offers Long-term Survival in Invasive Bladder Cancer (March 18, 2010)Combined modality therapy (CMT) preserves the bladder, achieves complete response (CR), and offers long-term survival in approximately 70% of patients with invasive bladder cancer, according to the results of a 15-year study presented at 2010 American... Continue Reading
More Stages II-III Bladder CancerStages II-III Breast Cancer
Study Evaluates Impact of Lymph Node Removal in Early-stage Breast Cancer (August 13, 2010)
Early-stage breast cancer patients without evidence of cancer in their sentinel lymph node who did not have additional lymph nodes removed report fewer side effects to the arm and breast than patients who undergo additional lymph node removal. These findings... Continue Reading
Updated Guidelines Address Hormonal Therapy for Breast Cancer (July 21, 2010)Among postmenopausal women with hormone receptor-positive breast cancer, use of an aromatase inhibitor at some point in the course of adjuvant (post-surgery) treatment results in a lower risk of cancer recurrence than use of tamoxifen only. Based on these... Continue Reading
Many Breast Cancer Patients Taking Adjuvant Hormonal Therapy Stop Treatment Early (July 1, 2010)Less than half of early-stage breast cancer patients with hormone-sensitive disease completed the full dose and schedule of their hormonal therapy treatment. These findings were recently published in the Journal of Clinical Oncology.[1] The majority of... Continue Reading
Racial Disparity in Breast Cancer Outcomes Among Underinsured (June 30, 2010)Underinsured African-Americans have worse breast cancer survival outcomes than their underinsured White counterparts, according to the results of a study published early online in the Journal of the National Caner Institute.[i] The disparity in breast... Continue Reading
Gene Mutation Increases Risk of Blood Clots in Breast Cancer Patients Taking Tamoxifen (June 29, 2010)Among women taking tamoxifen for early-stage breast cancer, an inherited gene mutation (Factor V Leiden) may increase the risk of blood clots. These results, which differ from a previous study that evaluated women taking tamoxifen for breast cancer prevention,... Continue Reading
More Stages II-III Breast CancerStages II-III Multiple Myeloma
Maintenance Therapy with Revlimid Slows Myeloma Progression (June 3, 2010)
Maintenance therapy with RevlimidÒ (lenalidomide) slowed disease progression by 54% among patients with multiple myeloma who had undergone high-dose chemotherapy and autologous stem cell transplantation. Interim results of this Phase III study will be... Continue Reading
Kepivance Reduces Toxicity of High-dose Therapy for Multiple Myeloma (March 24, 2010)Among patients undergoing high-dose therapy and autologous stem cell transplantation for multiple myeloma, a three-day short course of Kepivance® (palifermin) reduces the toxicity of treatment. These results were published in the Annals of Oncology. Multiple... Continue Reading
Benefit of Velcade on Myeloma Survival Added to Prescribing Information (March 5, 2010)The U.S. Food and Drug Administration (FDA) has approved expanded prescribing information for Velcade® (bortezomib). Velcade’s label now includes results from the VISTA study, which show that Velcade improves long-term overall survival among patients... Continue Reading
Addition of Velcade® and Revlimid® to Autologous Stem Cell Transplantation Produces Promising Results in Older Patients with Multiple Myeloma (January 7, 2010)In a Phase II clinical trial, treatment of older multiple myeloma patients with Velcade® (bortezomib) induction therapy, reduced-intensity tandem autologous stem cell transplantation, and Revlimid® (lenalidomide) consolidation-maintenance therapy produced... Continue Reading
Velcade® Improves Response Rate After High-dose Melphalan for Myeloma (December 21, 2009)Among patients who have received high-dose melphalan and an autologous stem cell transplant for initial treatment of multiple myeloma, Velcade® (bortezomib) appears to improve treatment response rates. These results were presented at the 2009 meeting... Continue Reading
More Stages II-III Multiple MyelomaStages II-IVA Cervical Cancer
Study Evaluates Incidence of Lymphedema Resulting from Cancer Treatment (August 9, 2010)
A systematic review of 47 studies evaluating treatment for melanoma, head and neck cancer, genitourinary cancers, gynecologic cancers, and sarcoma indicates that lymphedema is a common side effect of treatment for these diseases. These findings were recently... Continue Reading
Gemzar® Added to Chemoradiation Improves Survival in Locally Advanced Cervical Cancer (June 8, 2009)Gemzar® Added to Chemoradiation Improves Survival in Locally Advanced Cervical Cancer The combination of Gemzar® (gemcitabine), Platinol® (cisplatin), and concurrent radiation significantly improves survival over single-agent Platinol and radiation... Continue Reading
January Is National Cervical Cancer Awareness Month (March 8, 2009)January Is National Cervical Cancer Awareness Month As the month of January brings cervical cancer into focus, it’s a great time to increase public understanding of the disease, including its prevalence, approaches to screening and prevention, treatment... Continue Reading
Robotically-assisted Hysterectomy Appears Effective for Cervical Cancer (March 8, 2009)Robotically-assisted Hysterectomy Appears Effective for Cervical Cancer Robotically-assisted hysterectomy (RAH) in patients with early-stage cervical cancer is at least as effective as traditional open radical hysterectomy (ORH) and produces fewer complications,... Continue Reading
Differences in IMRT Radiation Doses May Complicate Study Results in Gynecological Cancers (March 8, 2009)Differences in IMRT Radiation Doses May Complicate Study Results in Gynecological Cancers Differences between the prescribed dose of radiation in intensity modulated radiation therapy (IMRT) and the dose that’s actually delivered may make comparison... Continue Reading
More Stages II-IVA Cervical CancerStages III-IV Gastric Cancer
Afinitor Promising in Treatment of Advanced Gastric Cancer (July 23, 2010)
Afinitor® (everolimus) may be a promising treatment option for patients with metastatic gastric cancer who have undergone previous treatment, according to a study published in the Journal of Clinical Oncology. Afinitor is an oral targeted therapy that... Continue Reading
Clinical Trial for Advanced Gastric Cancer Now Enrolling Patients (July 16, 2010)Gastric cancer forms in the tissues and lining of the stomach. Current treatment options include surgery, chemotherapy, and radiation. The current standard of care for metastatic gastric cancer is systemic therapy. Research is ongoing to determine which... Continue Reading
Depression May Persist With Metastatic Cancer (May 27, 2010)A substantial number of patients with metastatic cancer may suffer from depression which tends to persist and grow more severe toward the end of life, according to the results of a study published early online in the Journal of Clinical Oncology.[1] While... Continue Reading
Avastin Fails to Prolong Survival in Stomach Cancer (February 25, 2010)Avastin® (bevacizumab) in combination with chemotherapy does not extend overall survival in patients with inoperable, advanced or metastatic stomach cancer, according to the results of a phase III trial released by Roche.[i] Stomach cancer, also known... Continue Reading
Herceptin Improves Outcome of HER2-positive Stomach Cancer (October 3, 2009)According to the results of a Phase III clinical trial, treatment with the targeted therapy Herceptin® (trastuzumab) improves survival among patients with HER2-positive, advanced and inoperable stomach cancer. These results were presented at a major... Continue Reading
More Stages III-IV Gastric CancerStages IIIB-IV Lung Cancer - Non-Small Cell
Addition of Sutent to Tarceva Does Not Improve Overall Survival with Advanced Non-Small Cell Lung Cancer (September 7, 2010)
Among patients with previously treated non-small cell lung cancer, the combination of Sutent® (sunitinib) and Tarceva® (erlotinib) delays cancer progression but does not improve overall survival compared with Tarceva alone. The results of this Phase... Continue Reading
Early Palliative Care Linked with Longer Lung Cancer Survival (September 1, 2010)Palliative care is care that is focused on symptom management, psychosocial issues, decision-making, and quality of life. Among patients with newly diagnosed, metastatic, non-small cell lung cancer, the addition of early palliative care to standard cancer... Continue Reading
Study Evaluates Safety of Avastin and Chemotherapy in Non–Squamous Non–Small Cell Lung Cancer (August 3, 2010)A large Phase IV study confirms that the safety and efficacy reported in Phase III trials of Avastin® (bevacizumab) plus standard chemotherapy for patients with advanced non-squamous non-small cell lung cancer translate into the clinical practice setting.... Continue Reading
Large Study Confirms that Vandetanib Is Active in Previously Treated Non–Small Cell Lung Cancer (June 15, 2010)The combination of vandetanib plus Taxotere resulted in longer survival without cancer progression than Taxotere alone among patients with previously-treated non–small cell lung cancer (NSCLC). These findings were recently published in the journal The... Continue Reading
Combination Chemotherapy Improves Survival in Elderly Lung Cancer Patients (June 7, 2010)Among patients age 70 or older with advanced non-small cell lung cancer (NSCLC), treatment with a combination of two chemotherapy drugs—paclitaxel and carboplatin—results in better progression-free and overall survival than treatment with single-agent... Continue Reading
More Stages IIIB-IV Lung Cancer - Non-Small CellStem Cell Transplant
Complementary Therapy for Children Undergoing Stem Cell Transplant (July 19, 2010)
Complementary therapies such as massage and humor therapy may not help children cope with the potential emotional distress associated with stem cell transplantation, according to findings recently reported in Cancer. Stem cell transplantation involves... Continue Reading
Kepivance Reduces Toxicity of High-dose Therapy for Multiple Myeloma (March 24, 2010)Among patients undergoing high-dose therapy and autologous stem cell transplantation for multiple myeloma, a three-day short course of Kepivance® (palifermin) reduces the toxicity of treatment. These results were published in the Annals of Oncology. Multiple... Continue Reading
Statins May Reduce Acute Graft-versus-host Disease (March 8, 2009)Statins May Reduce Acute Graft-versus-host Disease Researchers from Ohio State University have reported that statins may reduce the risk of developing acute graft-versus-host disease (GVHD) among patients who undergo allogeneic stem cell transplants.... Continue Reading
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